Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Iberdomide (CC-220) is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 39.00 | |
2 mg | In stock | $ 55.00 | |
5 mg | In stock | $ 97.00 | |
10 mg | In stock | $ 172.00 | |
25 mg | In stock | $ 343.00 | |
50 mg | In stock | $ 612.00 | |
100 mg | In stock | $ 966.00 | |
200 mg | In stock | $ 1,290.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 96.00 |
Description | Iberdomide (CC-220) is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay). |
Targets&IC50 | cereblon:60 nM |
In vitro | Iberdomide has a greater potency for degrading the CRL4 complex substrates Ikaros and Aiolos (EC50s = 1 and 0.5 nM) but has no degradative activity for GSPT1 or CK1α[1]. |
Synonyms | CC-220 |
Molecular Weight | 449.5 |
Formula | C25H27N3O5 |
CAS No. | 1323403-33-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (66.74 mM)
You can also refer to dose conversion for different animals. More
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Iberdomide 1323403-33-3 Apoptosis PROTAC Ligand for E3 Ligase CELMoD H929 CRBN Ligands for E3 Ligase KMS12PE KMS11 orally sub-G1 CC 220 cereblon G0/G1 U266 multiple ligase Inhibitor Thalidomide RPM-8226 MM1.R MM1.S EJM KMS128M inhibit CC220 E3 ligase-recruiting Moiety myeloma CC-220 inhibitor