Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, induces the formation of a unipolar spindle phenotype, and mediates apoptosis. AZD-4877 has antitumor activity and inhibits circulating peripheral blood mononuclear cells (PBMC).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 293.00 | |
5 mg | In stock | $ 735.00 | |
10 mg | In stock | $ 987.00 | |
25 mg | In stock | $ 1,546.00 | |
50 mg | In stock | $ 1,980.00 | |
100 mg | In stock | $ 2,780.00 |
Description | AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, induces the formation of a unipolar spindle phenotype, and mediates apoptosis. AZD-4877 has antitumor activity and inhibits circulating peripheral blood mononuclear cells (PBMC). |
Targets&IC50 | EG5:2 nM |
Synonyms | AZD4877 |
Molecular Weight | 503.66 |
Formula | C28H33N5O2S |
CAS No. | 758722-49-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (109.2 mM)
You can also refer to dose conversion for different animals. More
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AZD-4877 758722-49-5 Apoptosis Cytoskeletal Signaling Kinesin AZD4877 AZD 4877 inhibitor inhibit