α-ketoglutarate — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T21024	Ornithine-α-ketoglutarate	L-Ornithine-α-ketoglutarate,Ornithine α ketoglutarate,L Ornithine α ketoglutarate,Ornithine α-ketoglutarate,OKG	Others
	Ornithine-α-ketoglutarate (L-Ornithine-α-ketoglutarate) is a salt formed of 2 molecules of ornithine and 1 alpha-ketoglutarate. Ornithine-α-ketoglutarate improves nutritional status in chronically malnourished (e.g., eld...		Others
T36871	5-Octyl-α-ketoglutarate
	In addition to its role in the Krebs cycle, α-ketoglutarate (2-oxoglutarate) has roles as a substrate or modulator of enzymes. 5-Octyl-α-ketoglutarate, also known as α-ketoglutarate octyl ester, is a stable, cell-permeab...
T9259	Alpha-calcium ketoglutarate monohydrate		Others
	Alpha-calcium ketoglutarate monohydrate is the calcium salt form of Alpha-ketoglutarate, which is involved in the tricarboxylic acid cycle in organisms.		Others
T71961	TUN-92046	DM-α-KG,T71961,Dimethyl 2-ketoglutarate,Dimethyl 2-oxoglutarate	Others
	TUN-92046 (Dimethyl 2-oxoglutarate) is a membrane-permeable alpha-ketoglutarate analogue that inhibits maladaptive autophagy in pressure overloading induced cardiomyopathy.		Others
T32080	Histidine oxoglurate	Histidine alpha-ketoglutarate
	Histidine oxoglurate is a bioactive chemical.
T71960	Aminogenistein
	Aminogenistein inhibits protein-tyrosine kinase activity of p56lck.
T6820	D-α-Hydroxyglutaric acid disodium	D-alpha-Hydroxyglutaric acid disodium salt,Disodium (R)-2-Hydroxyglutarate	ATPase , Others , Reactive Oxygen Species , Endogenous Metabolite , mTOR
	D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-Hydroxyglutarate) is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM.
T21634	N-Oxalylglycine	Oxalylglycine	Others
	N-Oxalylglycine (Oxalylglycine) is a cell permeable inhibitor of α-ketoglutarate-dependent enzymes.		Others
T36624L	α-Hydroxyglutaric Acid Lithium	α-Hydroxyglutaric Acid Lithium(2889-31-8 Free base)	Decarboxylase , Endogenous Metabolite , mTOR
	α-Hydroxyglutaric Acid Lithium, converted from glutamate in microorganisms and animals, is an inhibitor of α-ketoglutarate-dependent dioxygenase and 5-methylcytosine hydroxylase, and has an inhibitory effect on ATP synth...		Decarboxylase , Endogenous Metabolite , mTOR
T0200	α-Lipoic Acid	Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid	Apoptosis , NF-κB , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite
	α-Lipoic Acid (DL-α-Lipoic acid) an octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme ...
T1939	DMOG	Dimethyloxalylglycine,Dimethyloxallyl Glycine,Dimethyloxaloylglycine	HIF/HIF Prolyl-Hydroxylase , HIF , Autophagy
	DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.		HIF/HIF Prolyl-Hydroxylase , HIF , Autophagy
T13019	Succinyl phosphonate trisodium salt		Dehydrogenase , Reactive Oxygen Species , Endogenous Metabolite
	Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC)
TP1777L	P2Ca acetate(142606-55-1 free base)		Others
	p2Ca acetate is a naturally processed peptide that derives from a ubiquitous enzyme, alpha-ketoglutarate dehydrogenase, and is recognized in association with the class I MHC protein, Ld, by a CTL clone (2C).		Others
T6157	Devimistat	CPI-613,CPI613,CPI 613,6,8-Bis(benzylthio)octanoic acid	Apoptosis , Dehydrogenase , Mitochondrial Metabolism
	Devimistat (6,8-Bis(benzylthio)octanoic acid) , a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase, disrupts tumor cell mitochondrial metabolism. It has potent...		Apoptosis , Dehydrogenase , Mitochondrial Metabolism
T13020	Succinyl phosphonate		Others
	Succinyl phosphonate is a α-ketoglutarate dehydrogenase inhibitor .		Others
T77217	Saccharopine hydrochloride
	Saccharopine hydrochloride (L-Saccharopine hydrochloride), an intermediate in lysine degradation and a mitochondrial toxin, is produced through the conversion of lysine and α-ketoglutarate by lysine-ketoglutarate reducta...
T76174	Isocitrate dehydrogenase
	Isocitrate dehydrogenase (ICDH), a critical enzyme in the citric acid or tricarboxylic acid cycle, facilitates the oxidative decarboxylation of isocitrate to α-ketoglutarate while reducing NAD(P)+ to NAD(P)H, thus playin...
T38473	Malonyl Coenzyme A lithium
	Malonyl Coenzyme A (lithium) is a coenzyme A derivative that is utilized in fatty acid and polyketide synthesis and in the transport of α-ketoglutarate across the mitochondrial membrane. Malonyl Coenzyme A (lithium) is f...
T73616	Glutamate dehydrogenase (NAD(P))
	Glutamate dehydrogenase NAD(P) (GLDH), a mitochondrial enzyme located in hepatocytes, renal tissue, brain, muscle, and intestinal cells, catalyzes the reversible oxidative deamination of glutamate to α-ketoglutarate (α-K...
T76178	Aspartate aminotransferase
	Aspartate aminotransferase (AST) is a transaminase enzyme, is often used in biochemical studies. Aspartate aminotransferase catalyzes aspartate and alpha-ketoglutarate converts to oxaloacetate and glutamate. Aspartate am...