transporter — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T22714	Decynium 22		Others
	Decynium 22 is a plasma membrane monoamine transporter (PMAT) inhibitor		Others
T3713	BAY-876		transporter
	BAY-876 is an orally active and selective inhibitor of glucose transporter 1 (GLUT1, IC50= 2 nM). BAY-876 exhibits >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 also inhibits glycolytic metabol...		transporter
T9558	KL-11743		transporter
	KL-11743 specifically blocks glucose metabolism, triggering an acute collapse in NADH pools and a striking accumulation of aspartate, indicating a dramatic shift toward oxidative phosphorylation in the mitochondria.		transporter
T7147	Valbenazine	NBI-98854	Monoamine Transporter
	Valbenazine (NBI-98854), a highly selective vesicular monoamine transporter 2(VMAT2) inhibitor, is approved for the treatment of tardive dyskinesia.		Monoamine Transporter
T23070	Nisoxetine hydrochloride		Sodium Channel , Monoamine Transporter , Norepinephrine
	Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor		Sodium Channel , Monoamine Transporter , Norepinephrine
T9347	EAAT2 activator 1	3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine	transporter
	EAAT2 activator 1 (3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine) is a thiopyridazine derivative that has been found to increase EAAT2 protein levels in astrocytes.		transporter
T39429	AHN 1-055 hydrochloride	3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride	Dopamine Receptor
	AHN 1-055 hydrochloride (3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) is an inhibitor of dopamine transporter (DAT) and dopamine uptake(IC50 = 71 nM).		Dopamine Receptor
TN6552	5,7-Dimethoxyluteolin		Dopamine Receptor
	5,7-Dimethoxyluteolin is a natural product from Hovenia acerba. 5,7-Dimethoxyluteolin is a dopamine transporter (DAT) activator with an EC50 of 3.417 μM.		Dopamine Receptor
T11087	DOV-216,303 Free Base	DOV-216303	Dopamine Receptor , Serotonin Transporter , Norepinephrine
	DOV-216,303 Free Base (DOV-216303) is an inhibitor of serotonin, norepinephrine, and dopamine reuptake with with IC50s of 14, 20 and 78 nM. DOV-216,303 Free Base exhibits antidepressant effects.		Dopamine Receptor , Serotonin Transporter , Norepinephrine
T7018	WZB117		transporter
	WZB117 is a Glucose Transporter 1 (GLUT1) inhibitor. when IC50 of WZB117 approximate 10 μM, it inhibits lung cancer A549 cells and breast cancer MCF7 cells proliferation.		transporter
T15160	Dotinurad	(3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone	OAT
	Dotinurad ((3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone) is a potent agent of uricosuric (IC50: 3.6 μM for uric acid).		OAT
T12232	Nitroxazepine	CIBA 2330Go	Serotonin Transporter
	Nitroxazepine (CIBA 2330Go) is a serotonin-norepinephrine reuptake inhibitor, and treatment depression. Nitroxazepine is a tricyclic antidepressant (TCA) for the research of depression		Serotonin Transporter
T10758L	Centanafadine hydrochloride	EB-1020 hydrochloride	Dopamine Receptor , Serotonin Transporter , Adrenergic Receptor , Norepinephrine
	Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin...
T1768	7ACC2		Mitochondrial Metabolism , Monocarboxylate transporter
	7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for [14C]-lactate influx; new antitumor treatment targeting lactate transport in Y cells.		Mitochondrial Metabolism , Monocarboxylate transporter
T5208	BAY-8002	BAY8002,BAY 8002	Monocarboxylate transporter
	BAY-8002 is a potent dual MCT1/2 inhibitor (IC50 values are 3, 8, and 12 nM at rat (C6), human (DLD-1) and mouse (4T1) MCT1 respectively).		Monocarboxylate transporter
T8708	Paroxetine		Serotonin Transporter
	Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression.		Serotonin Transporter
T3210	AZD3965	AZD 3965,AZD-3965	Monocarboxylate transporter
	AZD3965 (AZD-3965) is a selective inhibitor of monocarboxylate transporter 1 (MCT1).		Monocarboxylate transporter
T3526	Dasotraline hydrochloride	SEP-225289 hydrochloride	Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine
	Dasotraline hydrochloride (SEP-225289 hydrochloride) (SEP-225289 hydrochloride) is a triple reuptake inhibitor that inhibits dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respe...
T15411	GPNA hydrochloride		Apoptosis , Others
	GPNA hydrochloride is specific glutamine (Gln) transporter ASCT2(SLC1A5) inhibitor. GPNA reversibly induces apoptosis in A549 cells. GPNA hydrochloride is a well-known substrate of the enzyme γ-glutamyltransferase (GGT)....		Apoptosis , Others
TN2252	Syrosingopine		Dopamine Receptor
	Syrosingopine has selective depleting effect on brain amines is potentiated by combined treatment with disulfiram or fusaric acid, a dopamine beta-hydroxylase inhibitor.		Dopamine Receptor