translation — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T22774L	Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]（TFA)		Others
	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) is Elongation factor 1 subunit.eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha sub...		Others
TP2247	Eukaryotic translation initiation factor 3		Others
	Eukaryotic initiation factors (eIF) are proteins involved in the initiation phase of eukaryotic translation. Eukaryotic translation initiation factor 3 binds to the ribosome subunit-mRNA complex. It has been implicated i...		Others
T50099	HIF-2α-IN-4		Others , HIF/HIF Prolyl-Hydroxylase
	HIF-2a translation inhibitor is a compound used as a molecular building block.		Others , HIF/HIF Prolyl-Hydroxylase
T22774	Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]		Others
	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. ...		Others
T16674	Pseudouridine		Endogenous Metabolite
	Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure.		Endogenous Metabolite
T5429	Theaflavin 3,3'-digallate	8-Gingerol,TFDG	Virus Protease , Antioxidant , HIV Protease , HSV
	Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul...		Virus Protease , Antioxidant , HIV Protease , HSV
T5331	KKL-35		Antibacterial
	KKL-35 is an inhibitor of trans-translation (IC50: 0.9 µM) with broad-spectrum antibiotic activity.		Antibacterial
T14886	Cbz-B3A		mTOR
	Cbz-B3A is a potent inhibitor of mTORC1 signalling, inhibits phosphorylation of eIF4E-binding protein 1 (4EBP1) and blocks translation by 68%.		mTOR
T3380	Homoharringtonine	Myelostat,Ceflatonin,HHT,Omacetaxine mepesuccinate	STAT
	Homoharringtonine (HHT) is a natural alkaloid that inhibits the translation of proteins and is cytotoxic. Homoharringtonine acts on the ribosomes of tumor cells to inhibit the elongation step of protein translation, ther...		STAT
T11511	Guanosine-5'-triphosphate disodium salt	5'-GTP disodium salt	Others , Endogenous Metabolite
	Guanosine-5'-triphosphate disodium salt (5'-GTP disodium salt) is an enhancer of myogenic cell differentiation and an energy source for translation and other important cellular processes.		Others , Endogenous Metabolite
T3265	Azathramycin	Desmethyl Azithromycin,6-Demethylazithromycin,Azaerythromycin A,Azaerythromycin	Antibacterial , Antibiotic
	Azathramycin (Desmethyl Azithromycin) is an antibiotic derived from erythromycin, binding to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA.		Antibacterial , Antibiotic
T22592	ATPγS tetralithium salt	ATP-gamma-S tetralithium salt	PERK
	ATPγS tetralithium salt is a substrate for nucleotide hydrolysis and RNA unraveling activity of the eukaryotic translation initiation factor eIF4A, associated with p97 mutants and prions.		PERK
T13767	MBX-4132		Others , Antibacterial
	MBX-4132, inhibit trans translation by binding to the bacterial ribosome,is a member of a chemical class called oxadiazoles.		Others , Antibacterial
T3147	Pyrrolidinedithiocarbamate ammonium	PDTC,Pyrrolidinedithiocarbamate,APDC,1-Pyrrolidinedithiocarboxylic acid ammonium salt,Ammonium pyrrolidinedithiocarbamate	NF-κB
	Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxide synthase mRNA to prevent induction.		NF-κB
T9980	AVJ16		IGF-1R
	AVJ16 as a member of the insulin growth factor 2 mRNA-binding protein family, binds to the mRNA of certain genes to regulate protein translation.		IGF-1R
T4058	R-IMPP		Others , Serine/threonin kinase
	R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.		Others , Serine/threonin kinase
T19459	N1-Methylpseudouridine	1-Methylpseudouridine	Others
	N1-Methylpseudouridine (1-Methylpseudouridine) is a methylpseudouridine and enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density in mRNA.		Others
T28543	RK-9123016	RK9123016,RK 9123016	Sirtuin
	RK-9123016 is a SIRT2 inhibitor. RK-9123016 increases the acetylation level of eukaryotic translation initiation factor 5A (eIF5A), a physiological substrate of SIRT2, and reduces cell viability of human breast cancer ce...		Sirtuin
T16702	QL47		Virus Protease , BTK
	QL47 is a host-targeted small molecule antiviral agent with antiviral activity against dengue and other RNA viruses.QL47 acts as an inhibitor of viral translation and a covalent inhibitor of BTK, and can be used in the s...		Virus Protease , BTK
T3052	Sancycline	Bonomycin,Norcycline,Sancyclinum,6-Demethyl-6-deoxytetracycline	Antibacterial
	Sancycline (Bonomycin) is a rare semi-synthetic tetracycline, acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site.		Antibacterial