tone — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1162	Acipimox	Olbemox,K-9321	Others
	Acipimox (K-9321) is a niacin derivative and nicotinic acid analog with activity as a hypolipidemic agent. Acipimox has special application for the treatment of hyperlipidemia in non-insulin-dependent diabetic patients.		Others
T8078	Gamma-decalactone	Decan-4-olide,γ-Decalactone	Others
	Gamma-decalactone (Decan-4-olide) is a food additive with a fruity peach flavor. Ricinoleic acid (12-hydroxy-octadec-9-enoic acid) is often used as a substrate in the production of γ-Decalactone.		Others
T9327	ω-Pentadecalactone	Cyclopentadecanolide,Oxacyclohexadecan-2-one,Exaltolide,Pentadecanolide	Others
	ω-Pentadecalactone (Exaltolide) is the fragrance structural group macrocyclic lactone and lactide derivatives used as a fragrance ingredient.		Others
TCS1709	BENZYLACETONE	4-Phenylbutan-2-one,Methyl 2-phenylethyl ketone,4-Phenyl-2-butanone	Tyrosinase
	Benzylacetone (4-Phenyl-2-butanone) is an aromatic compound extracted from incense wood. Benzylacetone has appetite-enhancing and exercise-reducing properties. Benzylacetone has a strong and reversible anti-mushroom tyro...		Tyrosinase
T0476	Spironolactone	SC9420,Abbolactone	Glucocorticoid Receptor , Androgen Receptor , Autophagy
	Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.		Glucocorticoid Receptor , Androgen Receptor , Autophagy
T25944	Phenoxyacetone	NSC-1876,NSC 1876,NSC1876	Others
	Phenoxyacetone (NSC-1876) is an inhibitor of acetylcholinesterase.		Others
T13965	Watermelon ketone	7-Methyl-2H-1,5-benzodioxepin-3(4H)-one	Others
	Watermelon ketone (7-Methyl-2H-1,5-benzodioxepin-3(4H)-one) is a fragrance compound, with a special odorant. It has been widely used in the fragrance industry.		Others
T14219	Aminaftone	Aminaphthone	Endothelin Receptor
	Aminaftone, a derivative of 4-aminobenzoic acid, inhibits endothelin-1 (ET-1) production and can be used to study hypertension and systemic sclerosis.		Endothelin Receptor
T4S0592	Toddalolactone	(+)-Toddalolactone	PAI-1
	Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic.		PAI-1
TN6744	Undecanoic gamma-lactone		Others
	Undecanoic gamma-lactone is a natural product.		Others
T25048	Algestone acetophenide	Neolutin	Others
	Algestone acetophenide (Neolutin) is progesterone that used in estrus synchronization and has been evaluated as an injectable contraceptive in combination with estradiol enanthate. It is also used therapeutically as a to...		Others
T11680	Isoasatone A		P450
	Isoasatone A is a natural product isolated from the plant Heterotropa takaoi M., with anti-insect activity.		P450
T12490	Pitavastatin lactone		Others
	Pitavastatin lactone is a major Pitavastatin metabolite in humans. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase little metabolized in hepatic microsomes.		Others
T13789	N-dodecanoyl-L-Homoserine lactone	C12-HSL	Others
	N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule, a microbial communication mechanism modulated by acyl homoserine lactone (AHL) molecules impacts biofilm formation in bioreactors.		Others
T16169	N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride	N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride	Others , Proteasome , COX
	N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride (N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride) is an inhibitor of trypsin-like protease. N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride exhib...		Others , Proteasome , COX
T6307	Lubiprostone	SPI-0211,RU-0211	Chloride channel
	Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.		Chloride channel
T3384	Wedelolactone	IKK Inhibitor II	Apoptosis , NF-κB , Lipoxygenase , Caspase
	Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.		Apoptosis , NF-κB , Lipoxygenase , Caspase
T41319	D-Saccharic acid 1,4-lactone hydrate		Others
	D-Saccharic acid 1,4-lactone hydrate is a potent β-glucuronidase inhibitor (IC50=48.4 μM). D-Saccharic acid 1,4-lactone hydrate possesses anticarcinogenic, detoxifying, and antioxidant properties[1][2].		Others
Fr12339	Anisylacetone		Others
	Anisylacetone (Anisylacetone) is an effective lure for the male melon fly.		Others
T11044	Dihydromunduletone	DHM	GPR
	Dihydromunduletone (DHM) is an adhesion G protein-coupled receptor (aGPCR) antagonist that acts as a chemical probe for the inhibition of GPR56 and GPR114/ADGRG5, which have similar tethered agonists.		GPR