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Search Results for " squalene "

20

Compounds

Cat No. Product Name Synonyms Targets
T4749 Squalene Nikko Squalane EX,Super Squalene,AddaVax,all-trans-Squalene,trans-Squalene,Spinacene Reactive Oxygen Species , Endogenous Metabolite , Antifungal
Squalene (AddaVax) is a natural organic compound originally obtained for commercial purposes primarily from shark liver oil, though there are botanical sources as well, including rice bran, wheat germ, and olives. All hi...
T75636 (E/Z)-Squalene (E/Z)-Super Squalene,(E/Z)-AddaVax
(E/Z)-Squalene ((E/Z)-AddaVax) regulates intracellular reactive oxidant species (ROS) production and induces apoptosis and necrosis in a concentration and time-dependent manner. (E/Z)-Squalene accumulates in the liver an...
TN5051 Squalene-2,3-diol Others
Squalene-2,3-diol is a natural product for research related to life sciences. The catalog number is TN5051 and the CAS number is 14031-37-9.
T81109 Squalene synthase-IN-1
Squalene synthase-IN-1 (compound 1) is a potent antihyperlipidemic agent that inhibits Squalene Synthase and demonstrates exceptional antioxidant and anti-inflammatory activities. It significantly reduces both glucose an...
TN1576 Diallyl disulfide IL Receptor , NOS , NF-κB
Diallyl disulfide has antitumor effect, the effect can be enhanced by miR-200b and miR-22.
T4066 FIN56 Ferroptosis
FIN56 is a specific inducer of ferroptosis.
T5613 Squalane Dodecahydrosqualene,Perhydrosqualene Others
Squalane (Perhydrosqualene) is a naturally occurring lipid in both plants and animals. It is usually used as a moisturizer and emollient in cosmetics manufacturing.
T1497 Liranaftate Piritetrate,M-732 Antifungal
Liranaftate (Piritetrate) is a thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in the synthesis of sterol which is ...
T6702 Terbinafine Terbinex,SF 86-327,Lamisil,TDT 067 Antibacterial , Antibiotic , Antifungal
Terbinafine (TDT 067) is a synthetic allylamine derivative with antifungal activity. Terbinafine exerts its effect through inhibition of squalene epoxidase, thereby blocking the biosynthesis of ergosterol, an important c...
T1411 Terbinafine hydrochloride KWD 2019,Terbinafine HCl,TDT 067 hydrochloride Antibacterial , Antibiotic , Antifungal
Terbinafine hydrochloride (KWD 2019) is a synthetic allylamine derivative structurally related to naftifine. Terbinafine is active against dermatophytes.
TN5134 Tetrahydroxysqualene Antifection
Tetrahdroxysqualene shows antimycobacterial activity with an MIC of 10.0 microg/mL, while showing only modest cytotoxicity.
TQ0115 NB-598 Antifungal
NB-598 is an effective and competitive inhibitor of squalene epoxidase. It suppresses triglyceride biosynthesis through the farnesol pathway.
T1217 Butenafine hydrochloride KP363 (Hydrochloride),Butenafine HCl,KP-363 Antibiotic , Antifungal
Butenafine hydrochloride (KP363 Hydrochloride) is a synthetic benzylamine antifungal, inhibiting the synthesis of sterols by inhibiting squalene epoxidase.
T11321 FR194738 free base Antifungal
FR194738 free base inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM. 
T1543 Naftifine hydrochloride Naftifungin,Naftifine HCl,Naftin,Exoderil Hedgehog/Smoothened , Antibiotic , Antifungal
Naftifine Hydrochloride is the hydrochloride salt form of naftifine, an allylamine derivate with synthetic broad-spectrum antifungal activity. Although the exact mechanism through which naftifine hydrochloride exerts its...
T83658 SQLE-IN-1 Antifungal
SQLE-IN-1 is a squalene epoxidase (SQLE) inhibitor with anti-tumor activity. It can inhibit the proliferation and migration of liver cancer cell line Huh7, inhibit the production of cellular cholesterol, and increase the...
T12765 RPR107393 free base Others
RPR107393 free base is a selective inhibitor of squalene synthase(rat liver microsomal squalene synthase, with an IC50 of 0.8 nM).
T25317 DF-461 DF 461
DF-461 is an inhibitor of squalene synthase.
T15709 Lapaquistat acetate TAK-475 Others
Lapaquistat acetate is a squalene synthase inhibitor. It also blocks the conversion of farnesyl diphosphate (FPP) to squalene. Lapaquistat acetate is used to Mevalonate Kinase Deficiency (MKD), it is effective at lowerin...
T13371 YM-53601 free base AMPK
YM-53601 free base is an inhibitor of squalene synthetase which suppresses lipogenic biosynthesis and lipid secretion in rodents.
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