screening — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T36421	Immuno-Oncology Screening Library
	The Immuno-Oncology Screening Library consists of 2 plates and contains more than 90 cancer and immunology-associated compounds in a 96-well Matrix tube rack format as 10 mM stock solutions in DMSO. This library include...
T11344	G150		DNA , cGAS
	G150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.G150 is an effective and highly selective inhibitor of human cyclic GMP-AMP synthase (H-CGAS).		DNA , cGAS
T21980	PD 198306		MEK
	PD 198306 is a selective inhibitor of MAPK/ERK-kinase (MEK) with antihyperalgesic effects. PD 198306 reduces the Streptozocin-induced increase in the level of active ERK1.		MEK
T17143	Toyocamycin	Vengicide	Apoptosis , Others , IRE1 , Antibiotic , Antifungal
	Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis.		Apoptosis , Others , IRE1 , Antibiotic , Antifungal
T13396	Zinc Protoporphyrin	Zinc Protoporphyrin-9,ZnPP,Zn(II)-protoporphyrin IX	Apoptosis , Reactive Oxygen Species , Endogenous Metabolite
	Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive inhibitor of heme oxygenase-1 (HO-1) and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2, and has anti-can...		Apoptosis , Reactive Oxygen Species , Endogenous Metabolite
T4925	Thiamine monophosphate chloride (dihydrate)	Thiamine monophosphate chloride dihydrat,Aneurine monophosphate chloride	Others , Endogenous Metabolite
	Thiamine monophosphate chloride dihydrate (Aneurine monophosphate chloride) is a compound used in the screening of ligands that promote protein stability		Others , Endogenous Metabolite
T67752	Compound V007-6018		Others
	Compound V007-6018 is a pharmaceutical compound used for drug screening.		Others
T4S0051	Coptisine sulfate		Indoleamine 2,3-Dioxygenase (IDO)
	1. Coptisine sulfate has growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program.		Indoleamine 2,3-Dioxygenase (IDO)
T9212	IMB-301		Others , HIV Protease
	IMB-301 is a small molecular inhibitor via virtual screening according to the hA3G model.		Others , HIV Protease
T4531	GSK2200150A		Antibacterial
	GSK2200150A is an anti-tuberculosis (TB) agent identified by high-throughput screening (HTS) campaign.		Antibacterial
T19340	Glutarylcarnitine	O-glutaroyl-L-carnitine	Endogenous Metabolite
	Glutarylcarnitine (O-glutaroyl-L-carnitine) is a diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes.		Endogenous Metabolite
T3572	NSC 15364	1,3-Bis(4-aminophenyl)urea,NSC15364	Apoptosis , Others , VDAC
	NSC 15364 (1,3-Bis(4-aminophenyl)urea) can be used for screening of ALR inhibitors by detection of hydrogen peroxide production Measured in Biochemical System.		Apoptosis , Others , VDAC
T24859	TC-AQP1-1		Aquaporin
	TC-AQP1-1 is a blocker of the aquaporin 1 channel identified by virtual screening and inhibits water flux through hAQP1 in Xenopus laevis oocyte swelling assays at low micromolar concentrations.		Aquaporin
T3313	D-Luciferin	Firefly luciferin,D-(-)-Luciferin	Others
	D-Luciferin (D-(-)-Luciferin) is a popular bioluminescent substrate of luciferase in the presence of ATP, used in luciferase-based bioluminescence imaging and cell-based high-throughput screening applications.		Others
TP1204	IRGD peptide	c(CRGDKGPDC)	Integrin
	iRGD peptide (c(CRGDKGPDC)) is a 9-amino acid cyclic peptide (sequence: CRGDKGPDC) and a molecular mimicry agent that was originally identified in an in vivo screening of phage display libraries in tumor-bearing mice.		Integrin
T4062	CAY10602		Sirtuin
	CAY10602 is a SIRT1 activator. CAY10602 was derived from high throughput screening for compounds that increase SIRT1-mediated deacetylation of a SIRT1-specific substrate. Functional assays show that CAY10602 dose-depende...		Sirtuin
T41256	SP-96		Aurora Kinase
	SP-96 is a highly effective and selective inhibitor of Aurora B with an IC50 of 0.316 nM. SP-96 shows selective growth inhibition in NCI60 screening, including MDA-MD-468 (GI50=107 nM). SP-96 can be used in triple negati...		Aurora Kinase
T3888	Scopolin	Murrayin,Scopoloside	Sirtuin
	Scopolin (Scopoloside) formation is increased by the enhanced activity of PAL. Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis, and this compound may be a potent agent for...		Sirtuin
T12258	NSC 601980 (analog)		Others
	NSC 601980 analog is the analog of the NSC601980 which shows antitumor activity in the yeast screening experiment.		Others
T25542	Isamfazone	Isamfazona,Isamfazonum
	Isamfazone is utilized in the chemical and pharmacological studies on substituted pyridazones, the discovery of novel anti-inflammatory agents by aligning screening.