Powder: -20°C for 3 years
In solvent: -80°C for 2 years
G150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.G150 is an effective and highly selective inhibitor of human cyclic GMP-AMP synthase (H-CGAS).
Description | G150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.G150 is an effective and highly selective inhibitor of human cyclic GMP-AMP synthase (H-CGAS). |
Targets&IC50 | h-cGAS:10.2 nM |
In vitro | G150 showed dose-dependent inhibitory activity in THP1 cells with cellular IC50 of 1.96?μM[1]. |
Molecular Weight | 391.25 |
Formula | C18H16Cl2N4O2 |
CAS No. | 2369751-30-2 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 120 mg/mL (306.71 mM), Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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G150 2369751-30-2 DNA损伤和修复 免疫与炎症 cGAS DNA human myeloid cell macrophage G 150 dsDNA THP1 Cyclic GMP-AMP Synthase Inhibitor G-150 anti-inflammatory high-throughput screening inhibit inhibitor