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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1117 | IFN-α Receptor Recognition Peptide 1 | IRRP1 | |
IFN-α Receptor Recognition Peptide 1, associated with receptor interactions, is a peptide of IFN-α. | |||
T8506 | THPP-1 | PDE | |
THPP-1 is a potent and orally bioavailable inhibitor of PDE10A(Ki of 1 nM and 1.3 nM for human and rat PDE10A, respectively). | |||
T8561 | Apcin | APC | |
Apcin is a potent and competitive inhibitor of anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substr... | |||
T28531 | Facinicline hydrochloride | RG3487 | 5-HT Receptor , AChR |
Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM). Facinicline hydrochloride improves cognition and sensorimot... | |||
T2306 | Brexpiprazole | OPC-34712 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Brexpiprazole (OPC-34712) is a partial agonist of human 5-hydroxytryptamine (5-HT) 5-HT1A and dopamine D2 receptors. | |||
T8690 | Brexpiprazole HCl | OPC 34712 dihydrochloride | Others |
Brexpiprazole HCl (OPC 34712 dihydrochloride) is a new antipsychotic drug. | |||
T60096 | EN106 | ZINC3888023 | Others |
EN106, a potent FEM1B inhibitor and a cysteine-reactive covalent ligand, effectively disrupts the recognition of FEM1B's crucial reductive stress substrate, FNIP1. | |||
T5474 | D159687 | D 159687 | PDE |
D159687 is a selective PDE4D inhibitor,had a procognitive profile as it improved memory in the novel object recognition test but had no antidepressant or anxiolytic benefit. | |||
T16816 | S 18986 | GluR | |
S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, showcasing cognitive-enhancing properties in rodents. It induces the release of noradrenaline and acetylcholine... | |||
T2783 | Methyl dihydrojasmonate | Methyl Dihydrojasmonate,Kharismal,Hedione | Others |
Methyl dihydrojasmonate (Kharismal) is an ester and a diffusive aroma compound, with the smell vaguely similar to jasmine. In racemic mixtures the odor is floral and citrus while epimerized mixtures exhibit a dense fatty... | |||
TP2131L | Rac1 Inhibitor W56 acetate(1095179-01-3 free base) | Rho | |
Peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction with Rac1-specific GEFs TrioN, GEF-H1 and Tiam1. | |||
T4S1999 | Valepotriate | Valtrate | Apoptosis , HIV Protease |
Valepotriate (Valtrate) fraction can have sedative effects and affect behavioral parameters related to recognition memory. Valepotriates, a new class of cytotoxic and antitumor agents, they are very potent cytotoxic agen... | |||
TP1570 | Cortistatin-14 | Somatostatin | |
Cortistatin-14, a neuropeptide structurally similar to growth inhibitor-14, has anticonvulsant and neuroprotective effects and impairs recognition memory consolidation in mice through activation of sst(2), growth hormone... | |||
T1638 | N-Acetylneuraminic acid | Acide aceneuramique,NeuAc,Lactaminic acid | Others , Influenza Virus , Endogenous Metabolite |
N-Acetylneuraminic acid (Acide aceneuramique) is a nine-carbon sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells. Studies have shown t... | |||
T8873 | Bractoppin | Others , DNA/RNA Synthesis | |
Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activi... | |||
T32191 | Irdabisant | CEP-26401,CEP 26401,CEP26401 | Histamine Receptor |
Irdabisant (CEP-26401) (CEP-26401) is a selective, orally active and blood-brain barrier (BBB) penetrant antagonist/inverse agonist of histamine H3 receptor (H3R) (rat H3R Ki= 7.2 nM, human H3R Ki= 2.0 nM). Irdabisant ex... | |||
T0910 | Terpin hydrate | Terpin Monohydrate,cis-Terpin hydrate | Others |
Terpin hydrate, a cis-form hydrate, is derived from sources such as oil of turpentine, oregano, thyme, and eucalyptus. It is used as an insect repellent and expectorant. Terpin hydrate(cis-Terpin hydrate) is commonly use... | |||
T34431 | RU 27849 | RU-27849,RU27849 | |
RU 27849 is used to study the binding of tryptamine recognition sites. | |||
T26100 | RLH 033 | RLH033,RLH-033 | |
RLH 033 is a selective ligand for the sigma 1 recognition site. | |||
T31040 | CP-18 F-18 | CP18 F-18,CP 18 F-18,(18F)-CP18 | |
CP-18 F-18 is a DEVD (the caspase 3 substrate recognition motif) that is an imaging tracer for caspase-3 activity in apoptotic cells. |