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CP-18 F-18

Catalog No. T31040   CAS 1193087-67-0
Synonyms: CP18 F-18, CP 18 F-18, (18F)-CP18

CP-18 F-18 is a DEVD (the caspase 3 substrate recognition motif) that is an imaging tracer for caspase-3 activity in apoptotic cells.

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CP-18 F-18 Chemical Structure
CP-18 F-18, CAS 1193087-67-0
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Biological Description
Chemical Properties
Storage & Solubility Information
Description CP-18 F-18 is a DEVD (the caspase 3 substrate recognition motif) that is an imaging tracer for caspase-3 activity in apoptotic cells.
Synonyms CP18 F-18, CP 18 F-18, (18F)-CP18
Molecular Weight 1152.13
Formula C46H73FN10O23
CAS No. 1193087-67-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Chen SF, Wei TZ, Rao LY, Xu MG, Dong ZL. CT-1-CP-induced ventricular electrical remodeling in mice. J Huazhong Univ Sci Technolog Med Sci. 2015 Feb;35(1):21-7. doi: 10.1007/s11596-015-1383-8. Epub 2015 Feb 12. PubMed PMID: 25673188. 2. Coleman A, Weir KA, Ware RS, Boyd RN. Relationship between communication skills and gross motor function in preschool-aged children with cerebral palsy. Arch Phys Med Rehabil. 2013 Nov;94(11):2210-7. doi: 10.1016/j.apmr.2013.03.025. Epub 2013 Apr 11. PubMed PMID: 23583864. 3. Abe Y, Tamura K, Sakata I, Ishida J, Fukuba I, Matsuoka R, Shimizu S, Murakami H, Machida K. Usefulness of (18)F-FDG positron emission tomography/computed tomography for the diagnosis of pyothorax-associated lymphoma: A report of three cases. Oncol Lett. 2010 Sep;1(5):833-836. Epub 2010 Sep 1. PubMed PMID: 22966389; PubMed Central PMCID: PMC3436407. 4. Thie JA. Volume-normalized uptake rates with robust transportability from PET dual-time and Patlak analyses. Mol Imaging Biol. 2010 Oct;12(5):479-87. doi: 10.1007/s11307-009-0280-6. Epub 2009 Dec 1. PubMed PMID: 19949982.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

CP-18 F-18 1193087-67-0 CP18 F18 CP18 F-18 CP 18 F-18 CP 18 F 18 (18F)-CP18 inhibitor inhibit

 

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