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20

Compounds

Cat No. Product Name Synonyms Targets
T22891 KL001 KL 001,KL-001 Others
KL 001 is a Cryptochrome protein (CRY) stabilizer. KL001 prevented ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. KL001-mediated CRY stabilization inhibited glucagon-induced glu...
T13485 2-Phenylglycine DL-α-Phenylglycine Endogenous Metabolite
2-Phenylglycine (DL-α-Phenylglycine) is a metabolite in breast milk during the lactation period.
T19538 (R)-(-)-1,3-Butanediol Endogenous Metabolite
(R)-(-)-1,3-Butanediol is a novel ketogenic ester that rapidly increases circulating concentrations of r- and s-ß-hydroxybutyric acid in healthy adults in a short period of time and can be used to study metabolic system-...
T9608 KL201 Others
KL201 a circadian clock modulator, is a isoform-selective cryptochrome 1 (CRY1) stabilizer. KL201 lengthens the period of circadian rhythms in cells and tissues[1].
T0518 Methacycline hydrochloride Rondomycin,Methacycline HCl ribosome , Antibacterial , Antibiotic
Methacycline hydrochloride (Rondomycin) is a broad-spectrum semisynthetic antibiotic related to TETRACYCLINE but excreted more slowly and maintaining effective blood levels for a more extended period.
T0905 Pyrithioxin Pyridoxine disulfide,Encefabol,Vitamin B6 disulfide,Pyritinol,Bonifen Others , Endogenous Metabolite
Pyrithioxin (Encefabol) is a neurodynamic compound, combined with a short period of hyperventilation (HV) was applied in cerebral infarct patients with Hemiplegia. Pyrithioxin is regarded as an encephalotropic or nootrop...
T9356 (E/Z)-GO289 Casein Kinase
(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2. (E/Z)-GO289 exhibited cell type-dependent inhibition of cancer cell growth that correlated with cellular clock function...
T6476 Dofetilide UK 68789,UK-68798,Tikosyn Potassium Channel
Dofetilide (UK 68789) is a sulfonamide class III antiarrhythmic agent and potassium channel blocker. Dofetilide selectively blocks cardiac ion channels of the rapid component of the delayed rectifier potassium current Ik...
T5294 (S)-Leucic acid L-LEUCIC ACID,Hydroxyisocaproic acid,(S)-(−)-2-Hydroxyisocaproic acid Others , Endogenous Metabolite
(S)-Leucic acid (Hydroxyisocaproic acid) is an end product of leucine metabolism in human tissues such as muscle and connective tissue. It belongs to 2-hydroxycarboxylic acid group of amino acid metabolites. (S)-Leucic a...
T60777 EM127 ERK , Histone Methyltransferase
EM127 is a highly selective and potent covalent inhibitor of SMYD3 with a KD value of 13 μM.EM127 inhibits ERK1/2 phosphorylation and inhibits transcriptional regulation of SMYD3 target genes.EM127 slowly reduces methylt...
T4947 3-Hydroxybutyric acid Butanoic acid Endogenous Metabolite
3-Hydroxybutyric acid (Butanoic acid) (or beta-hydroxybutyrate) is a ketone body. Like the other ketone bodies (acetoacetate and acetone), levels of 3-hydroxybutyrate in blood and urine are raised in ketosis. In humans, ...
T0866 Propafenone Rythmol,Propafenonum Potassium Channel , MRP , Sodium Channel
Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity....
T4881 Phosphorylethanolamine O-Phosphorylethanolamine Others , Endogenous Metabolite
Phosphorylethanolamine (O-Phosphorylethanolamine) is a phosphomonoester metabolite of the phospholipid metabolism. Phosphorylethanolamine is a precursor of phospholipid synthesis and a product of phospholipid breakdown. ...
T37821 AP 14145 hydrochloride
KCa2 (small conductance Ca2+-activated potassium) channel negative allosteric modulator (IC50 = 1.1 μM). Increases the EC50 of Ca2+ on KCa2.3 channels by ~3-fold. Prolongs atrial effective refractory period (AERP) in rat...
T80849 VU661
VU661, a redox-active phenazine carboxamide, modulates circadian rhythms by inducing period lengthening.
T29000 Tralomethrin EPA Pesticide Chemical Code 121501,SAGA,HAG-107,HAG 107,Scout
Tralomethrin is used as a pyrethroid insecticide. It modifies the gating kinetics of the sodium channels in neurons, increases the length of time the channel remains open after a stimulus, thereby depolarizing the neuron...
T37773 Tetranor-PGEM tetranor-Prostaglandin E Metabolite,tetranor-PGEM
tetranor-PGEM is the major urinary metabolite of PGE1 and PGE2, and is used as a marker of PGE2 biosynthesis.[1],[2] About 15% of an infused dose of PGE2 appears as this metabolite in the urine of humans. Normal healthy ...
T36916 Estrone-3-Glucuronide (sodium salt hydrate)
Estrone-3-Glucuronide is a metabolite of the primary premenopausal estrogen 17β-estradiol .1,2Urinary levels of estrone-3-Glucuronide peak approximately 36 hours prior to ovulation and have been used as a marker of ferti...
T68502 Dibrospidium Free Base
Dibrospidium Free Base is a dispirotripiperazine derivative and alkylating agent with potential antineoplastic and anti-inflammatory activities. The duration of DNA synthesis inhibition in tumor cells was found to correl...
T62942 Moricizine Hydrochloride
Moricizine Hydrochloride (EN 313) is an orally active class I antiarrhythmic agent that reduces the maximum rate of phase 0 depolarisation; increases the repolarisation rate of phases 2 and 3, reduces the duration of act...

Compounds

KL001
T22891
Synonym: KL 001,KL-001
Target: Others
2-Phenylglycine
T13485
Synonym: DL-α-Phenylglycine
Target: Endogenous Metabolite
(R)-(-)-1,3-Butanediol
T19538
Synonym:
Target: Endogenous Metabolite
KL201
T9608
Synonym:
Target: Others
Methacycline hydrochloride
T0518
Synonym: Rondomycin,Methacycline HCl
Target: ribosome, Antibacterial, Antibiotic
Pyrithioxin
T0905
Synonym: Pyridoxine disulfide,Encefabol,Vitamin B6 disulfide,Pyritinol,Bonifen
Target: Others, Endogenous Metabolite
(E/Z)-GO289
T9356
Synonym:
Target: Casein Kinase
Dofetilide
T6476
Synonym: UK 68789,UK-68798,Tikosyn
Target: Potassium Channel
(S)-Leucic acid
T5294
Synonym: L-LEUCIC ACID,Hydroxyisocaproic acid,(S)-(−)-2-Hydroxyisocaproic acid
Target: Others, Endogenous Metabolite
EM127
T60777
Synonym:
Target: ERK, Histone Methyltransferase
3-Hydroxybutyric acid
T4947
Synonym: Butanoic acid
Target: Endogenous Metabolite
Propafenone
T0866
Synonym: Rythmol,Propafenonum
Target: Potassium Channel, MRP, Sodium Channel
Phosphorylethanolamine
T4881
Synonym: O-Phosphorylethanolamine
Target: Others, Endogenous Metabolite
AP 14145 hydrochloride
T37821
Synonym:
Target:
VU661
T80849
Synonym:
Target:
Tralomethrin
T29000
Synonym: EPA Pesticide Chemical Code 121501,SAGA,HAG-107,HAG 107,Scout
Target:
tetranor-PGEM
T37773
Synonym: tetranor-Prostaglandin E Metabolite,tetranor-PGEM
Target:
Estrone-3-Glucuronide (sodium salt hydrate)
T36916
Synonym:
Target:
Dibrospidium Free Base
T68502
Synonym:
Target:
Moricizine Hydrochloride
T62942
Synonym:
Target:
1 2
TargetMol