Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KL 001 is a Cryptochrome protein (CRY) stabilizer. KL001 prevented ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. KL001-mediated CRY stabilization inhibited glucagon-induced gluconeogenesis in primary hepatocytes. KL001 thus provides a tool to study the regulation of CRY-dependent physiology and aid development of clock-based therapeutics of diabetes.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 32.00 | |
5 mg | In stock | $ 80.00 | |
10 mg | In stock | $ 116.00 | |
25 mg | In stock | $ 198.00 | |
50 mg | In stock | $ 293.00 | |
100 mg | In stock | $ 438.00 | |
500 mg | In stock | $ 983.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 89.00 |
Description | KL 001 is a Cryptochrome protein (CRY) stabilizer. KL001 prevented ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. KL001-mediated CRY stabilization inhibited glucagon-induced gluconeogenesis in primary hepatocytes. KL001 thus provides a tool to study the regulation of CRY-dependent physiology and aid development of clock-based therapeutics of diabetes. |
Synonyms | KL 001, KL-001 |
Molecular Weight | 398.48 |
Formula | C21H22N2O4S |
CAS No. | 309928-48-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 65 mg/ml (163.12 mM)
You can also refer to dose conversion for different animals. More
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KL001 309928-48-1 Others Inhibitor KL 001 inhibit stabilizer KL-001 circadian cryptochrome ubiquitin period gluconeogenesis CRY inhibitor