pancreatic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1137L	Pancreatic Polypeptide (human) acetate		Neuropeptide Y Receptor
	Pancreatic Polypeptide (human) acetate is a C-terminally amidated 36 amino acid peptide, which acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist.		Neuropeptide Y Receptor
TP1044L	Pancreatic Polypeptide, rat acetate		Neuropeptide Y Receptor
	Pancreatic Polypeptide, rat acetate is an agonist of NPY receptor, with high affinity at NPYR4.		Neuropeptide Y Receptor
TP1044	Pancreatic Polypeptide, rat	Rat pancreatic polypeptide
	Pancreatic Polypeptide, rat is an agonist of NPY receptor, with high affinity at NPYR4. Pancreatic polypeptide (PP) is a 36-amino acid, C-terminally amidated peptide, and is a member of the PP-fold peptide family. It is ...
TP1137	Pancreatic Polypeptide, human	Human pancreatic polypeptide
	Endogenous high affinity agonist for human NPY Y4 receptor (Ki = 0.056 nM). Believed to play an important role in the function of the gastrointestinal tract.
T0517	Pancreatin	Pancreatic enzymes,pancrelipase	Others
	Pancreatin (pancrelipase) is a mixture of several digestive enzymes secreted by the exocrine cells of the pancreas. It is composed of amylase, lipase and protease.		Others
TP1731	Pancreatic Polypeptide, bovine
	Agonist at Y4 neuropeptide Y receptors.
T3359	Aprotinin	Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin	Others , Serine Protease , Influenza Virus , Proteasome
	Aprotinin (Traskolan) a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, kallikrein, plasmin, tissue plasminogen activat...		Others , Serine Protease , Influenza Virus , Proteasome
T76538	Pancreatic polypeptide
	Pancreatic polypeptide, a peptide produced by the pancreas's endocrine PP cells, modulates pancreatic secretory functions and influences hepatic glycogen levels and gastrointestinal secretion [1].
T63015	Pancreatic lipase/Carboxylesterase 1-IN-1
	Pancreatic lipase/Carboxylesterase 1-IN-1 (Compound 39) is a potent, dual inhibitor of pancreatic lipase (PL) and human carboxylesterase 1A (hCES1A), acting on PL (IC50: 2.13 μM) and hCES1A (IC50: 0.055 μM).
T5S0777	Phellodendrine chloride		Others
	Phellodendrine chloride has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli.		Others
T8439	Clobenpropit dihydrobromide		Apoptosis , Histamine Receptor
	Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07)		Apoptosis , Histamine Receptor
T9693	TBAP-001		Raf
	TBAP-001 is a RAF kinase inhibitor, with an IC50 of 62 nM in BRAF V600E kinase assay and an IC50 of 18 nM in Cell-Based Phosho-ERK Assay.		Raf
T5469	K-Ras-IN-1		Raf , Ras
	K-Ras-IN-1 is a K-Ras inhibitor.		Raf , Ras
T8982	RH01687		Others
	RH01687 is a potent β-cell protector , exhibits β-cell-protective activities against endoplasmic reticulum (ER) stress.		Others
T9050	AG-270		Others , Methionine Adenosyltransferase (MAT)
	AG-270 is an allosteric and orally active inhibitor of MAT2A.		Others , Methionine Adenosyltransferase (MAT)
T10255	AES-135		HDAC
	AES-135 is a potent HDAC inhibitor, inhibits HDAC3, HDAC6, HDAC11 (IC50s: 654, 190, and 636 nM) with anti-tumor activity.		HDAC
T21773	SP-141	SP 141	Mdm2
	SP 141 is a MDM2 inhibitor.SP-141 promotes MDM2 auto-ubiquitination and degradation, with anticancer activity.		Mdm2
T2613	Almorexant	ACT 078573	OX Receptor
	Almorexant (ACT 078573) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively.		OX Receptor
T2055	WS3		EGFR , IκB/IKK
	WS3, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.		EGFR , IκB/IKK
TN2269	Tetramethylcurcumin		Apoptosis , STAT
	Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also inhibits colony formation in soft agar, cell invasion, and e...		Apoptosis , STAT