painful — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T19723	AMTB hydrochloride	AMTB	TRP/TRPV Channel
	AMTB hydrochloride (AMTB HCl) is a novel TRPM8 channel blocker and is effective for pain and urinary diseases. AMTB can act on the bladder afferent pathway to attenuate the bladder micturition reflex and nociceptive refl...		TRP/TRPV Channel
T0378	Oxybuprocaine hydrochloride	Risedronic Acid,Oxybuprocaine HCl	Sodium Channel
	Oxybuprocaine hydrochloride (Oxybuprocaine HCl), a local anesthetic, is used especially in otolaryngology and ophthalmology.		Sodium Channel
T30824	Cgp 29030A	Cgp29030A,Cgp-29030A	Others
	CGP 29030A is a new piperazine derivative with analgesic activity and significant inhibitory effect on potentially nociceptive dorsal horn neurons, which can be used to study painful disorders.		Others
T72282	Ebaresdax hydrochloride		Endogenous Metabolite
	Ebaresdax hydrochloride has analgesic activity and is used in the study of painful diabetic neuropathy caused by type I or type II diabetes.		Endogenous Metabolite
T1303	Auranofin	SKF-39162	Others , SARS-CoV , Antibacterial
	Auranofin (SKF-39162) is an antirheumatic agent, is used to treat rheumatoid arthritis, improves arthritis symptoms including painful or tender and swollen joints and morning stiffness.		Others , SARS-CoV , Antibacterial
T15273	Fedovapagon	VA483,A106483	Vasopressin Receptor
	Fedovapagon (VA106483) is a selective and potent agonist of the vasopressin V2 receptor (V2R) that inhibits the growth of intersegmental vessels in zebrafish. Fedovapagon can be used to study overactive bladder, nocturia...		Vasopressin Receptor
T7177	Capsazepine		Apoptosis , TRP/TRPV Channel
	Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM). Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of chilli pepper) which activates the TRPV1 ion channel. It is ...		Apoptosis , TRP/TRPV Channel
T67805	Oxepinac
	oxepinac is an effective and well-tolerated compound for the treatment of painful osteoarthritis. oxepinac has no teratogenic effect on mouse and rabbit fetuses in animal experiments.
T1409	Methocarbamol	Lumirelax,Metocarbamol,AHR 85,Robaxin	Sodium Channel , Carbonic Anhydrase
	Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful musc...		Sodium Channel , Carbonic Anhydrase
T0219	Valdecoxib	SC 65872	COX
	Valdecoxib (SC 65872) is a prescription drug used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms. It is classified as a nonsteroidal anti-inflammatory drug, or N...		COX
T25616	Lanepitant 2HCl	LY303870 dihydrochloride,LY 303870 dihydrochloride,LY-303870 dihydrochloride,Lanepitant dihydrochloride	Neurokinin receptor
	Lanepitant 2HCl is a non-peptide neurokinin-1 receptor antagonist with analgesic and anti-inflammatory activity.Lanepitant 2HCl inhibits the binding of Substance P to the neurokinin-1 receptor, inhibits neurogenic inflam...		Neurokinin receptor
T3S0209	Vincristine		ERK , p38 MAPK , NF-κB , Akt , JNK , mTOR
	Vincristine binds to tubulin and inhibits the formation of microtubules, thereby inhibiting mitosis of the cancer cell. Vincristine can be used as a microtubule-destabilizing agent for research on the treatment of hemato...		ERK , p38 MAPK , NF-κB , Akt , JNK , mTOR
T28778	Silperisone HCl	RGH5002,SILA336,RGH-5002,Silperisone hydrochloride,SILA-336
	Silperisone HCl (RGH-5002) blocks sodium and calcium channels in cells, decreases excitability and contractility of muscle cells, reduces peripheral tone, and acts as a muscle relaxant and peripheral vasodilator. Silperi...