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Lanepitant 2HCl

Catalog No. T25616 CAS 170508-05-1

Synonyms: LY303870 dihydrochloride, LY 303870 dihydrochloride, LY-303870 dihydrochloride, Lanepitant dihydrochloride

Lanepitant 2HCl is a non-peptide neurokinin-1 receptor antagonist with analgesic and anti-inflammatory activity.Lanepitant 2HCl inhibits the binding of Substance P to the neurokinin-1 receptor, inhibits neurogenic inflammation and pain transmission, and can be used in the study of painful neuropathic disorders, such as migraines.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Lanepitant 2HCl, CAS 170508-05-1

Pack Size	Availability	Price/USD
1 mg	In stock	$ 195.00
5 mg	In stock	$ 483.00
10 mg	In stock	$ 692.00
25 mg	In stock	$ 1,080.00
50 mg	In stock	$ 1,490.00
100 mg	In stock	$ 1,970.00

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Purity: 98.89%

ee: 100%

Biological Description

Chemical Properties

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Description

Synonyms	LY303870 dihydrochloride, LY 303870 dihydrochloride, LY-303870 dihydrochloride, Lanepitant dihydrochloride
Molecular Weight	632.66
Formula	C33H47Cl2N5O3
CAS No.	170508-05-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Goldstein DJ,et al. Lanepitant, an NK-1 antagonist, in migraine prevention. Cephalalgia. 2001 Mar;21(2):102-6. 2. Goldstein DJ, et al. Study of the analgesic effect of lanepitant in patients with osteoarthritis pain. Clin Pharmacol Ther. 2000 Apr;67(4):419-26. 3. Goldstein DJ, et al. Dose-response study of the analgesic effect of lanepitant in patients with painful diabetic neuropathy. Clin Neuropharmacol. 2001 Jan-Feb;24(1):16-22. 4. Bignami F, et al. NK1 receptor antagonists as a new treatment for corneal neovascularization. Invest Ophthalmol Vis Sci. 2014 Sep 16;55(10):6783-94.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Lanepitant 2HCl 170508-05-1 GPCR/G Protein Neuroscience Neurokinin receptor LY303870 dihydrochloride LY-303870 Lanepitant HCl LY 303870 Lanepitant LY303870 LY 303870 dihydrochloride LY-303870 dihydrochloride Lanepitant dihydrochloride inhibitor inhibit

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