nonsteroidal — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T61444	Nonsteroidal aromatase inhibitor 1
	Nonsteroidal aromatase inhibitor 1 (Compound 13h) effectively inhibits the enzyme CYP19A1 with an IC50 value of 0.09 nM. Due to its potent inhibitory activity, Nonsteroidal aromatase inhibitor 1 holds promise for researc...
T19823	Tebufenozide		Apoptosis
	Tebufenozide is a novel nonsteroidal ecdysone agonist. It shows good efficacy and playing an increasingly important role in the control of Lepidopteran pests.		Apoptosis
T8575	ENFENAMIC ACID		Platelet aggregation
	Enfenamic acid is a platelet aggregation inhibitor and with antirheumatic.		Platelet aggregation
T7436	Cilofexor		FXR , Autophagy
	Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.		FXR , Autophagy
T28362	PF-02413873	PF02413873	Progesterone Receptor
	PF-02413873 is a competitive antagonist of nonsteroidal progesterone receptor with a Ki of 2.6 nM. PF-02413873 can be used in studies about the treatment of gynecological conditions such as endometriosis.		Progesterone Receptor
T0291	Flurbiprofen	dl-Flurbiprofen	Apoptosis , COX , MRP
	Flurbiprofen (dl-Flurbiprofen) is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.		Apoptosis , COX , MRP
T12832	Amcenestrant	SAR439859	Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	Amcenestrant (SAR439859) is an orally active, nonsteroidal and selective degrader of estrogen receptor (SERD). SAR439859 is a potent antagonist of ER (with an EC50 of 0.2 nM for ERα degradation).		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T4561	Tiaprofenic acid	Tiaprofensaeure,Acido tiaprofenico,Surgam	Others , COX
	Tiaprofenic acid (Acido tiaprofenico) is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain.		Others , COX
T6533	Hexestrol	Bibenzyl,Hexanoestrol,meso-Hexestrol,Hexestrofen	Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	Hexestrol (Hexanoestrol) binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively.		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T36683	Vedaprofen	Quadrisol,PM 150,CERM 10202	COX , Antibacterial , Prostaglandin Receptor
	Vedaprofen (PM 150) inhibits COX-1 and reduces prostaglandin H2 synthesis with anti-inflammatory activities. Vedaprofen is an inhibitor of Escherichia coli sliding clamp with the IC50 of 222 μM and Ki of 131 μM.		COX , Antibacterial , Prostaglandin Receptor
T0459	Sulindac	Arthrocine,MK-231,Clinoril,Sulindac sulfoxide	COX , Autophagy
	Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cycl...		COX , Autophagy
T21395	Finerenone	BAY948862,BAY-948862,BAY94-8862,BAY 94-8862,BAY-94-8862,BAY 948862	Glucocorticoid Receptor
	Finerenone (BAY-948862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM for the treatment of chronic heart failure. Finerenone (BAY-948862...		Glucocorticoid Receptor
T1280	Nepafenac	AL 6515,AHR 9434	COX
	Nepafenac (AHR 9434) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of nepafenac is as a Cyclooxygenase Inhibitor. The chemical classification of nepafenac is Nonsteroidal Anti-inflammatory Compounds.		COX
T13184	Topilutamide	Fluridil,BP766	Others
	Topilutamide (Fluridil) is a topical nonsteroidal antiandrogen.		Others
T2550	Tolmetin	Tolectin	COX
	Tolmetin (Tolectin) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of tolmetin is as a Cyclooxygenase Inhibitor. The chemical classification of tolmetin is Nonsteroidal Anti-inflammatory Compounds.		COX
T0826	Meloxicam	Movalis,Mobic,Metacam	Apoptosis , COX , Autophagy
	Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of meloxicam is as a Cyclooxygenase Inhibitor. The chemical classification of meloxicam is Nonsteroidal Anti-inflammatory Compounds.		Apoptosis , COX , Autophagy
T0708	Oxaprozin	Oxaprozinum,Wy21743	NF-κB , COX
	Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of oxaprozin is as a Cyclooxygenase Inhibitor. The chemical classification of oxaprozin is Nonsteroidal Anti-inflammatory Compound...		NF-κB , COX
T6497	Fenoprofen Calcium		Others , COX
	Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.		Others , COX
T28454	Proquazone	Proquazona,Arthrex,Proquazonum,Biarison	Others
	Proquazone (Arthrex) is a nonsteroidal anti-inflammatory agent.		Others
T25956	Piketoprofen	Calmatel	Others
	Piketoprofen (Calmatel) is a topical nonsteroidal anti-inflammatory agent.		Others