Shopping Cart
- Remove All
Your shopping cart is currently empty
PF-02413873
🥰Excellent
Catalog No. T28362Cas No. 936345-35-6
Alias PF02413873
PF-02413873 is a competitive antagonist of nonsteroidal progesterone receptor with a Ki of 2.6 nM. PF-02413873 can be used in studies about the treatment of gynecological conditions such as endometriosis.
PF-02413873
🥰Excellent
Purity: 100%
Catalog No. T28362Alias PF02413873Cas No. 936345-35-6
PF-02413873 is a competitive antagonist of nonsteroidal progesterone receptor with a Ki of 2.6 nM. PF-02413873 can be used in studies about the treatment of gynecological conditions such as endometriosis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $34 | In Stock | |
| 2 mg | $46 | In Stock | |
| 5 mg | $80 | In Stock | |
| 10 mg | $128 | In Stock | |
| 25 mg | $263 | In Stock | |
| 50 mg | $422 | In Stock | |
| 100 mg | $628 | In Stock | |
| 500 mg | $1,350 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $89 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "PF-02413873"
Vilaprisan
BAY10-02670, BAY-10-02670, BAY-1002670, BAY1002670, BAY 10-02670, BAY 1002670
T350541262108-14-4In house
Vilaprisan (BAY 1002670) is a novel orally available and selective progesterone receptor modulator (SPRM) with antiproliferative activity against uterine fibroids (UF) and can be used for the study of uterine fibroids.
- $195
Size
QTY
Norethindrone acetate
19-Norethindroneacetate
T4059851-98-9
Norethindrone acetate (19-Norethindroneacetate) is an oestrogen with inhibitory effects on adolescent menstruation and hepatic adenomas and is often used in combination with progestins in the study of endometriosis.
- $31
Size
QTY
Progesterone
Cited
Pregn-4-ene-3,20-dione
T047857-83-0
Progesterone (Pregn-4-ene-3,20-dione) is the major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production.
- $38
Size
QTY
CitedUlipristal acetate
Ulipristal, CDB-2914
T2527126784-99-4
Ulipristal acetate (CDB-2914) is an orally bioavailable selective progesterone receptor modulator with anti-progesterone activity. It binds to the progesterone receptor (PR), inhibiting PR-mediated gene expression and interfering with progesterone activity in the reproductive system, potentially suppressing the growth of uterine leiomyomatosis. Additionally, ulipristal can be used as emergency contraception by inhibiting or delaying ovulation and affecting endometrial tissue.
- $45
Size
QTY
Mifepristone Cited
RU486, RU 38486, C-1073
T110284371-65-3
Mifepristone (C-1073) is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist.
- $37
Size
QTY
CitedDydrogesterone
T3036152-62-5
Dydrogesterone is a potent progestogen which can be used in progesterone deficiency studies.
- $31
Size
QTY
Levonorgestrel
D-Norgestrel
T1263797-63-7
Levonorgestrel (D-Norgestrel) is a Progestin and Progestin-containing Intrauterine Device. The physiologic effect of levonorgestrel is by means of Inhibit Ovum Fertilization.
- $42
Size
QTY
Medroxyprogesterone Acetate Cited
Provera, NSC-26386, Metigestrona, Medroxyprogesterone 17-acetate, Medroxyprogesterone (acetate), Farlutin
T126171-58-9
Medroxyprogesterone Acetate (Farlutin) is a synthetic progestin that is derived from 17-hydroxyprogesterone. It is a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been used to treat breast and endometrial neoplasms.
Androgen ReceptorEndogenous MetaboliteEstrogen/progestogen ReceptorGlucocorticoid ReceptorProgesterone Receptor
- $30
Size
QTY
CitedEthynodiol diacetate Cited
Ethynodiol acetate, 8080 CB
T0996297-76-7
Ethynodiol diacetate (Ethynodiol acetate) is a synthetic progestational hormone utilized alone or combined with estrogens as an oral contraceptive.
- $35
Size
QTY
CitedNorethindrone Cited
Norethisterone
T151468-22-4
Norethindrone (Norethisterone) is a synthetic progestational hormone with actions similar to those of PROGESTERONE but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The hormone has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for contraception.
- $38
Size
QTY
CitedAltrenogest
RU2267, R2267, Allyltrenbolone, A35957
T0870850-52-2
Altrenogest (Allyltrenbolone)(A35957; RU2267), a progestogen, has structural relation with veterinary steroid trenbolone.
- $45
Size
QTY
Etonogestrel
Nexplanon, Implanon, 3-Oxodesogestrel, 3-keto-Desogestrel
T256754048-10-1
Etonogestrel (Implanon) is a steroidal progestin used as hormonal contraceptives.
- $32
Size
QTY
Select Batch
Purity:100%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | PF-02413873 is a competitive antagonist of nonsteroidal progesterone receptor with a Ki of 2.6 nM. PF-02413873 can be used in studies about the treatment of gynecological conditions such as endometriosis. |
| Targets&IC50 | Progesterone receptor:2.6 nM (Ki) |
| In vitro | PF-02413873 induces nuclear translocation only at high concentrations (>3 μM). PF-02413873 shows a derived Ki of 9.7 nM in the T47D native functional assay[3]. |
| In vivo | In cynomolgus macaques, PF-02413873 (3 mg/kg; p.o.) exhibits a t1/2 of 4.2 h, a Cmax of 162 ng/mL and CL/F of 41 mL/min/kg. PF-02413873 (2.5 and 10 mg/kg; p.o.) reduces the endometrial thickness of 43 and 56%, respectively[3]. |
| Alias | PF02413873 |
| Molecular Weight | 359.44 |
| Formula | C18H21N3O3S |
| Cas No. | 936345-35-6 |
| Smiles | Cc1c(Oc2cc(C)c(C#N)c(C)c2)c(nn1CS(C)(=O)=O)C1CC1 |
| Relative Density. | 1.31 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 95 mg/mL (264.30 mM), Sonication and heating to 60℃ are recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Sci Citations
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy PF-02413873 | purchase PF-02413873 | PF-02413873 cost | order PF-02413873 | PF-02413873 chemical structure | PF-02413873 in vivo | PF-02413873 in vitro | PF-02413873 formula | PF-02413873 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.