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Search Results for " neurogenesis "

13

Compounds

Cat No. Product Name Synonyms Targets
T8778 TTK21 Epigenetic Reader Domain
TTK21 is an activator of CBP/p300 histone acetyltransferase activity.
T0084 Moclobemide Ro111163 MAO , Monoamine Oxidase
Moclobemide (Ro111163) is a reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
T2003 ISX-9 Isoxazole 9,Isoxazole 9 (ISX-9) Calcium Channel , Wnt/beta-catenin
ISX-9 (Isoxazole 9) is necessary to activate neuron-specific genes as neurogenesis inducer.
T69601 ER272
ER272 is a natural PKC activator, inducing hippocampal neurogenesis.
T35546 Yhhu 3792
Notch signaling pathway activator; enhances the self-renewal capability of neural stem cells (NSCs) via Notch signaling pathway activation in vitro and in vivo. Promotes the expression of Notch target genes, Hes3 and Hes...
T68665 Yonkenafil Tunodafil
Yonkenafil (Tunodafil), a novel phosphodiesterase 5 (PDE5) inhibitor, effectively reduces cerebral infarction, neurological deficits, edema, and neuronal damage in the infarcted area. It potentially enhances cognitive fu...
T78023 MR 409
MR 409, a selective growth hormone-releasing hormone (GHRH) agonist, exhibits notable neuroprotective properties by augmenting endogenous neurogenesis in cerebral ischemic mice and demonstrates the ability to inhibit in ...
T75944 Spadin TFA
Spadin TFA, a natural peptide originating from a propeptide in blood, acts as a powerful TREK-1 channel inhibitor with an IC 50 of 10 nM. It boosts dorsal raphe nucleus 5-HT neurotransmission in mice, activates hippocamp...
T38100 Betamethasone 21-phosphate (sodium salt hydrate)
Betamethasone 21-phosphate is a synthetic glucocorticoid.1It prevents increases in macrophage and eosinophil numbers in bronchoalveolar lavage fluid (BALF) and decreases in blood leukocyte numbers in a guinea pig model o...
T35552 Ganglioside GD3 Mixture (sodium salt)
Ganglioside GD3 is synthesized by the addition of two sialic acid residues to lactosylceramide and can serve as a precursor to the formation of more complex gangliosides by the action of glycosyl- and sialyltransferases....
T61930 Yhhu-3792
Yhhu-3792 activates Notch signaling pathway and promotes the expression of Hes3 and Hes5. Yhhu-3792 enhanced the self-renewal ability of neural stem cells (NSCs), expanded the NSC pool and promoted endogenous neurogenesi...
T60395 Nrf2-ARE/hMAO-B/QR2 modulator 1
Nrf2-ARE/hMAO-B/QR2 modulator 1 is a new resveratrol-based multitarget-directed ligands (MTDLs) that showed a well-balanced MTDL profile: cellular activation of the NRF2-ARE pathway (CD = 9.83 μM), selective inhibition o...
TN2775 2-Methoxystypandrone MMP , BCL , IκB/IKK , GSK-3 , TNF , NOS , NF-κB , Wnt/beta-catenin , COX , JAK , STAT
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflammation and oxidative stress for preservation of BBB integrit...
TargetMol