movement — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T16980	Taminadenant		Adenosine Receptor
	Taminadenant is an adenosine receptor antagonist.		Adenosine Receptor
T9522	Rimtuzalcap	CAD-1883	Potassium Channel
	Rimtuzalcap (CAD-1883) (CAD-1883), a pioneering selective positive allosteric modulator of small-conductance calcium-activated potassium channels (SK channels), is employed in the study of movement disorders such as spin...		Potassium Channel
T12877L	Seltorexant	JNJ-42847922	OX Receptor
	Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain. Seltorexant is a high-affinity and selective orexin-2 receptor antagonist (pKi: 8.0 and 8.1 for human a...		OX Receptor
T7943	Fluphenazine decanoate		Dopamine Receptor
	Fluphenazine decanoate is dopamine D2 receptor blocke,and is a long-acting phenothiazine neuroleptic that used to treat schizophrenia.		Dopamine Receptor
T71138L	Binospirone	MDL 73005EF	5-HT Receptor
	Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of glaucoma and movement disorders associated with neurologic dysfunction.		5-HT Receptor
T0719	Tetrabenazine	Xenazine,Ro 1-9569	Others , Dopamine Receptor , Monoamine Transporter
	Tetrabenazine (Ro 1-9569) is a drug formerly used as an antipsychotic and treatment of various movement disorders. Tetrabenazine blocks neurotransmitter uptake into adrenergic storage vesicles and has been used as a high...		Others , Dopamine Receptor , Monoamine Transporter
T72170	NaV1.2/1.6 channel blocker-1		Sodium Channel
	NaV1.2/1.6 channel blocker-1 is a potent NaV1.2/1.6 channel blocker with inhibitory effects on rNaV1.6 and hNaV1.2.NaV1.2 channel blocker-1 can be used in the study of generalised epilepsy and movement disorders.		Sodium Channel
T67882	(2R,3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-ol		Others
	(2R,3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-ol is an impurity of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder.		Others
T1776L	Plerixafor octahydrochloride	JM3100 octahydrochloride,Plerixafor 8HCl (AMD3100 8HCl),Plerixafor 8HCl,SID791 octahydrochloride,AMD 3100 octahydrochloride,JM 3100 8HCl	Virus Protease , HIV Protease , CXCR
	Plerixafor octahydrochloride (JM3100 octahydrochloride) blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting in hematopoietic stem cell (HSC) release from bone marrow a...		Virus Protease , HIV Protease , CXCR
T1751	Eliprodil	SL-820715	NMDAR , iGluR
	Eliprodil (SL-820715)(SL-820715), a non-competitive NR2B-NMDA receptor antagonist(IC50: 1 uM), less effective for NR2A- and NR2C-containing receptors(IC50> 100 uM). It has been used in trials studying the treatment of Pa...		NMDAR , iGluR
T2162	Maribavir	BW1263W94,GW257406X,Benzimidavir,1263W94	Others , HCV Protease
	Maribavir (GW257406X) is an orally available benzimidazole riboside compound with activity against cytomegalovirus (CMV). Maribavir is a selective ATP competitor of the viral UL97 kinase, which is involved in viral nucle...		Others , HCV Protease
T16811	RWJ-51204		GABA Receptor
	RWJ-51204 is a selective adenosine A2A receptor antagonist and a partial agonist of GABA(A) receptor (IC50: 0.2-2 nM). It has neuroprotective and movement-improving effects and can be used in research related to Parkinso...		GABA Receptor
T10826	CK-666		HIV Protease , Microtubule Associated
	CK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex. It binds to the Arp2/3 complex, stabilizes the inactive state of the complex, blocking the movement of the Arp2 and Arp3 subunits into the act...		HIV Protease , Microtubule Associated
TN5801	12-Hydroxyjasmonic acid
	12-Hydroxyjasmonic acid glucoside is a COI1-JAZ-independent activator of leaf-closing movement in samanea saman.
T31264	Deanol acetamidobenzoate	Deanol p-acetamidobenzoate,Elevan,Diforene,Cervoxan,Deaner
	Deanol acetamidobenzoate is CNS stimulant. It can be caused elevated blood choline levels, can be used in Treatment of Choreiform Movement Disorders.
T2507L2	Azeliragon HCl	TTP488 HCl,Azeliragon hydrochloride,TTP 488,Azeliragon dihydrochloride,TTP-488
	Azeliragon is a potent and orally active inhibitor of RAGE (receptor for advanced glycation endproducts), a pattern recognition receptor, which affects the movement of amyloid, an Alzheimer's-associated protein, into the...
T26260	Tetrabenazine methanesulfonate	NSC169886,NSC 169886,NSC-169886
	Tetrabenazine methanesulfonate is a medicine formerly utilized as an antipsychotic and therapy for various movement disorders. Tetrabenazine methanesulfonate blocks neurotransmitter uptake into adrenergic storage vesicle...
TN5330	Lacinilene C	3,10-Dihydroxy-1,3,5,7-cadinatetraen-9-one
	Lacinilene C, lacinilene C 7-methyl ether, scopoletin, 2-hydroxy-7-methoxycadalene and 2,7-dihydroxycadalene are 5 induced phytoalexins in cotton leaves. Lacinilene C methyl ether elicits contraction of TSM by enhancing ...
T68216	Sanguiin h 11
	Sanguiin h 11 is a compound purified from the plant Sanguisorba officinalis and has proven to be a potent inhibitor of chemoattractant-dependent and independent neutrophil movement.
T26342	YH16899	YH-16899,YH 16899,BC-K-YH16899
	YH16899 is a KRS-67LR interaction inhibitor by directly blocking the association between KRS and 67LR, suppressing the dynamic movement of the N-terminal extension of KRS and reducing membrane localization of KRS.