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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T35862 | Cucurbit[8]uril | Others | |
Cucurbit[8]uril is a highly effective and safe supramolecular compound that promotes protein heterodimerization. It selectively induces the heterodimerization of methylviologen and naphthalene functionalized proteins, de... | |||
T21246 | Metsulfuron-methyl | Others | |
Metsulfuron-methyl is a systemic selective wheat field high-efficiency sulfonylurea herbicide, which mainly controls most broadleaf weeds and grass weeds in wheat fields. | |||
T7413 | JNJ-5207852 | Histamine Receptor | |
JNJ-5207852 is a novel, non-imidazole histamine H3 receptor antagonist, with high affinity at the rat (pKi=8.9) and human (pKi=9.24) H3 receptor. | |||
T9193 | ACH-000143 | Melatonin Receptor , MT Receptor | |
ACH-000143 have been identified as a novel agonist of the melatonin receptors MT1 and MT2. | |||
T8646 | URB937 | FAAH | |
URB937 is an inhibitor of FAAH and increases anandamide levels(IC50 : 26.8 nM). | |||
T13950 | UC-514321 | Apoptosis , STAT | |
UC-514321 directly targets STAT3/5 and represses TET1 expression. UC-514321 has the potential to treat acute myeloid leukemia (AML) both in vitro and in vivo, with low toxicity. | |||
T9050 | AG-270 | Others , Methionine Adenosyltransferase (MAT) | |
AG-270 is an allosteric and orally active inhibitor of MAT2A. | |||
T8418 | DCLK1-IN-1 | Others | |
DCLK1-IN-1 is a selective and in vivo-compatible chemical probe of the DCLK1 kinase domain . | |||
T7057 | Methylstat | Histone Demethylase , Others | |
Methylstat is a methyl ester prodrug of a Jumonji C domain-containing histone demethylase (JMJD) inhibitor that has favorable cell permeability. The free acid of methylstat inhibits JMJD2A, JMJD2C, JMJD2E, PHF8, and JMJD... | |||
T13974 | ZL0580 | Epigenetic Reader Domain , HIV Protease | |
ZL0580 induces HIV suppression by inhibiting Tat transactivation and transcription elongation as well as by inducing repressive chromatin structure at the HIV promoter. | |||
T2086 | ELN-441958 | ELN 441958 | Bradykinin Receptor |
ELN-441958 is a potent, neutral antagonist of B1 receptor, inhibits the binding of the B1 agonist ligand [3H]DAKD to IMR-90 cells with Ki of 0.26 nM. ELN-441958(ELN 441958) is highly selective for B1 over B2 receptors. | |||
T5S0246 | Pseudoprotodioscin | Others , Fatty Acid Synthase | |
1. Pseudoprotodioscin has moderate cytotoxicity. | |||
T10565 | BMS-1001 hydrochloride | PD-1/PD-L1 | |
BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activat... | |||
T9575 | MRTX9768 | Histone Methyltransferase | |
MRTX-9768 is a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target MTAP/CDKN2A-deleted tumors. | |||
T7860 | SM-324405 | SM 324405 | TLR |
SM-324405 is an agonist of TLR7. | |||
T1115 | Doxylamine succinate | Decapryn | Histamine Receptor |
Doxylamine Succinate is a pyridine derivate histamine H1 antagonist with pronounced sedative properties. Doxylamine succinate (Decapryn) competitively blocks the histamine H1 receptor and limits the typical allergic and ... | |||
T9812 | Tubulin inhibitor 24 | Microtubule Associated | |
Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization. | |||
T4325 | COTI-2 | COTI 2,COTI2 | Apoptosis , p53 |
COTI-2, an orally available thiosemicarbazone, is an activator of mutant forms of the p53 protein with potential antineoplastic activity. | |||
T33639 | Neotame | NC 00723,HSDB 7965,NC-00723,NC00723 | Others |
Neotame (HSDB 7965) is a white-colored, dipeptide methyl ester, which is found to be a highly potent and non-nutritive sweetener or flavour enhancer and hence finds applications in a variety of foods. | |||
T19031 | NBD-F | 4-Fluoro-7-nitrobenzofurazan | Others |
NBD-F (4-Fluoro-7-nitrobenzofurazan) is a fluorescent derivatization compound for amino acid analysis. |