ligand — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T17870	CIAP1 ligand 1	E3 ligase Ligand 12	Others
	cIAP1 ligand 1 (E3 ligase Ligand 12) is an apoptotic protein ligand based on the LCL161 derivative that recruits IAP ubiquitin ligases to degrade target proteins, and can be used to couple with androgen receptor ligands ...		Others
T10053	5HT6-ligand-1		5-HT Receptor
	5HT6-ligand-1 is an orally active ligand of 5-HT6 receptor (Ki = 1.43 nM).		5-HT Receptor
TP1484L	α2β1 Integrin Ligand Peptide acetate	α2β1 Integrin Ligand Peptide acetate (134580-64-6)	Integrin
	α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) is a potential antagonist of α2β1 integrin receptor. α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the...		Integrin
T13510	Sigma-LIGAND-1		Sigma receptor
	Sigma-LIGAND-1 is a selective Sigma Receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 has a Ki of 4000 nM at the dopamine D2 receptor.		Sigma receptor
T5835	PROTAC ERRα ligand 2		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	PROTAC ERRα ligand 2 is an estrogen-related receptor α (ERRα) inverse agonist( IC50 : 5.67 nM)		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T15191	PROTAC ERRα ligand 1		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	PROTAC ERRα ligand 1 is an α (ERRα) antagonist of estrogen-related receptor (IC50s of 0.04 and 2.8 μM for ERRα and ERRγ, respectively).		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T12551	PROTAC BRD4 ligand-1		Epigenetic Reader Domain , Ligands for Target Protein for PROTAC
	PROTAC BRD4 ligand-1 is a ligand for BRD4 for Protac GNE-987 and an inhibitor of BET.
T17879	E3 ligase Ligand 8		Others , Ligand for E3 Ligase
	E3 ligase Ligand 8 is a ligand for E3 ubiquitin ligase. The E3 ligase Ligand 8 can be linked to protein ligands through linkers to form PROTACs, which are inducers of ubiquitination-mediated degradation of cancer-promoti...		Others , Ligand for E3 Ligase
TP1704	Galanin Receptor Ligand M35 TFA		Neuropeptide Y Receptor
	Galanin Receptor Ligand M35 TFA is a high-affinity ligand and antagonist of galanin receptor (Kd=0.1 nM).		Neuropeptide Y Receptor
T38476	Metallo β-lactamase ligand 1		Antibacterial
	Metallo β-lactamase ligand 1 is an inhibitor of class B β-lactamase exhibiting antibacterial activities.		Antibacterial
T60015	TSPO ligand-2	Carbonic acid	AUTACs
	TSPO ligand-2 (Carbonic acid) is a ligand of AUTAC1 which contains a p-fluorobenzylguanine and a Fumagillol moiety.		AUTACs
T9809	E3 ligase Ligand 23		Ligand for E3 Ligase
	E3 ligase Ligand 23 is a cereblon binder and degrades Ikaros or Aiolos through ubiquitin proteasome.		Ligand for E3 Ligase
TP1496L	P5 Ligand for Dnak and DnaJ acetate	p5 Ligand for Dnak and DnaJ acetate(209518-24-1 free base)	HSP
	p5 Ligand for Dnak and DnaJ acetate is a nonapeptide. It is a high-affinity ligand for DnaK (E. coli Hsp70) and DnaJ (E. coli Hsp40).		HSP
T13848	SMARCA-BD ligand 1 for Protac		Epigenetic Reader Domain
	SMARCA-BD ligand 1 for Protac is a compound capable of binding to SMARCA2, the BAF ATPase subunit, based on the Protac technology for degrading SMARCA2		Epigenetic Reader Domain
T9360	CRBN ligand-9	2-(2,6-dioxopiperidin-3-yl)-5-nitroisoindoline-1,3-dione	Ligand for E3 Ligase
	CRBN ligand-9 (2-(2,6-dioxopiperidin-3-yl)-5-nitroisoindoline-1,3-dione) exhibit inhibition of CRBN.		Ligand for E3 Ligase
T13890	SMARCA-BD ligand 1 for Protac dihydrochloride		Epigenetic Reader Domain
	SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.		Epigenetic Reader Domain
T73599	TSPO ligand-1		Autophagy
	TSPO ligand-1 has affinity for peripheral and central benzodiazepine receptors.TSPO ligand-1 is an AUTAC4-binding protein in the transmembrane domain of the outer mitochondrial membrane, which induces mitochondrial autop...		Autophagy
T39628	PROTAC BRD4 ligand-2	PROTAC BRD4 ligand-2
	PROTAC BRD4 ligand-2 is a ligand for target BRD4 protein for PROTAC CFT-2718.
T39997	PROTAC CDK9 ligand-1	PROTAC CDK9 ligand-1
	PROTAC CDK9 ligand-1 is a CDK9 ligand that can be used in the synthesis of PROTACs.
T82174	HRIO2 kinase ligand-1		Others
	hRIO2 kinase ligand-1 is a potent ligand for hRIO2 kinase (Kd: 520 nM).		Others