Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5HT6-ligand-1 is an orally active ligand of 5-HT6 receptor (Ki = 1.43 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 329.00 | |
5 mg | In stock | $ 798.00 | |
10 mg | In stock | $ 1,090.00 | |
25 mg | In stock | $ 1,650.00 | |
50 mg | In stock | $ 2,230.00 | |
100 mg | In stock | $ 2,930.00 |
Description | 5HT6-ligand-1 is an orally active ligand of 5-HT6 receptor (Ki = 1.43 nM). |
Targets&IC50 | 5-HT6(ki):ki:1.43 nM |
In vivo | 5HT6-ligand-1(10 mg/kg) reverses the time delay-induced memory deficit and improves cognitive ability. 5HT6-ligand-1 shows an oral t1/2 of 3.17 h, a Cmax of 60 ng/mL, an exposure of 217 ng h/mL, and a bioavailability of 29%. Intravenous administration of 5HT6-ligand-1 exhibits a clearance of 220 mL/min/kg and a volume of distribution of 32.6 L/kg[1]. |
Molecular Weight | 448.38 |
Formula | C20H22BrN3O2S |
CAS No. | 1038988-11-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (22.3 mM)
You can also refer to dose conversion for different animals. More
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5HT6-ligand-1 1038988-11-2 GPCR/G Protein Neuroscience 5-HT Receptor 5HT6 ligand 1 5HT-6-ligand-1 5HT6ligand1 inhibitor inhibit