Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sigma-LIGAND-1 is a selective Sigma Receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 has a Ki of 4000 nM at the dopamine D2 receptor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 163.00 | |
5 mg | In stock | $ 422.00 | |
10 mg | In stock | $ 628.00 | |
25 mg | In stock | $ 981.00 | |
50 mg | In stock | $ 1,350.00 | |
100 mg | In stock | $ 1,820.00 | |
500 mg | In stock | $ 3,630.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 488.00 |
Description | Sigma-LIGAND-1 is a selective Sigma Receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 has a Ki of 4000 nM at the dopamine D2 receptor. |
Targets&IC50 | DTG site of sigma receptor:16 nM , σ receptor (PPP site):19 nM |
In vivo | Administration of Sigma-LIGAND-1 would reverse amphetamine-induced hyperlocomotion in mice, a behavioral model sensitive to antipsychotic compounds[1]. |
Molecular Weight | 435.56 |
Formula | C27H33NO4 |
CAS No. | 139652-01-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90 mg/mL (206.6 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Sigma-LIGAND-1 139652-01-0 GPCR/G Protein Sigma receptor σ-LIGAND-1 SigmaLIGAND1 Sigma LIGAND 1 inhibitor inhibit