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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6335 | Tie2 kinase inhibitor 1 | Tie2 kinase inhibitor | Tie-2 |
Tie2 kinase inhibitor 1 (Tie2 kinase inhibitor), an optimized compound of SB-203580, is selective to Tie2 with IC50 of 0.25 μM, which is 200-fold more effective than p38. | |||
T5524 | Aurora kinase inhibitor-3 | Aurora Kinase Inhibitor III | Aurora Kinase |
Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR. | |||
T4191 | Multi-kinase inhibitor 1 | Multi-kinase inhibitor I | Others , Bcr-Abl , PDGFR , c-Kit |
Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor. | |||
T9040 | Aurora kinase inhibitor-2 | IUN-70219,Aurora Kinase Inhibitor II | Aurora Kinase |
Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M). | |||
T10276L | AKT Kinase Inhibitor HCl | AKT Kinase Inhibitor HCl(842148-40-7 Free base) | Akt |
AKT Kinase Inhibitor HCl is an Akt inhibitor with antitumor activity. | |||
T11184 | EML4-ALK kinase inhibitor 1 | EML4 ALK kinase inhibitor 1,EML4-ALK kinase inhibitor 1 | ALK |
EML4-ALK kinase inhibitor 1 (EML4 ALK kinase inhibitor 1) is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM. | |||
T60108 | PDGFR Tyrosine Kinase Inhibitor III | PDGF Receptor Tyrosine Kinase Inhibitor III | PDGFR |
PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III) (PDGF Receptor Tyrosine Kinase Inhibitor III) is a multikinase inhibitor that inhibits PDGFR, EGFR, FGFR, PKA, and PKC, respectively. PDGF... | |||
T16987 | TAO Kinase inhibitor 1 | Others , MAPK | |
TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death. TAO Kinase inhibitor 1 is a selective and ATP-competitive thousand-and-one amino acid kinases inhibitor (IC50s: 11 to 15 nM for TAOK1 and 2, respectiv... | |||
T8864 | Thymidylate Kinase Inhibitor, YMU1 | Others | |
YMU1 is a human thymidylate kinase (hTMPK) inhibitor. YMU1 stabilizes the conformation of ligand-induced degradation (LID) region of hTMPK and blocks the catalytic site or ATP-binding site. | |||
TP1053L | Protein Kinase C 19-31 acetate | Protein Kinase C 19-31 acetate(121545-65-1 free base),PKC (19-31) acetate | PKC |
Protein Kinase C 19-31 acetate, a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is... | |||
T12728 | RIP2 Kinase Inhibitor 3 | Others , RIP kinase | |
RIP2 Kinase Inhibitor 3 is a potent and selective inhibitor of RIP2 with an IC50 of 1 nM. | |||
T12721 | Rho-Kinase-IN-1 | ROCK | |
Rho-Kinase-IN-1 is an inhibitor of ROCK with Kis of 30.5 nM and 3.9 nM for ROCK1 and ROCK2, respectively. Rho-Kinase-IN-1 can be used in studies about excessive cell proliferation, remodeling, edema and inflammation dise... | |||
T4692 | Protein kinase inhibitors 1 hydrochlorid | Protein kinase inhibitors 1 hydrochlorid (1365986-44-2(free base)) | Others |
Protein kinase inhibitors 1 hydrochlorid (Protein kinase inhibitors 1 hydrochlorid (1365986-44-2(free base))) is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM. | |||
T9564 | IRE1α kinase-IN-1 | IRE1 | |
IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM. It displays 100-fold selectivity for IRE1α over the IRE1β isoform. It inhibits ER stress-induced IRE1α oligomerization and autophosph... | |||
T10687 | Casein Kinase II Inhibitor IV | Casein Kinase | |
Casein Kinase II Inhibitor IV is an inducer of epidermal keratinocyte differentiation. | |||
T10276 | AKT Kinase Inhibitor | Akt | |
AKT Kinase Inhibitor is an Akt inhibitor with antitumor activity that selectively inhibits cell proliferation in a dose-dependent manner. | |||
T64350 | Casein kinase 1δ-IN-3 | Casein Kinase | |
Casein kinase 1δ-IN-3 (Casein kinase 1δ-IN-3) (Compound 23a) is a casein kinase 1 delta (CK1d) inhibitor with a pIC50 of 6.5376 M. | |||
TP1051L | Protein Kinase C Peptide Substrate acetate | Protein Kinase C Peptide Substrate acetate(120253-69-2 free base) | Others |
Protein Kinase C Peptide Substrate acetate targets specific cell spacers ina manner that is dependent on second messengers and specific adaptor proteins in response to extracellular signals that activate g protein-couple... | |||
T6409 | ALK kinase inhibitor-1 | SAR348830 | Others |
SAR348830 is an ALK inhibitor, targeting anaplastic lymphoma kinase. | |||
T77500 | Casein kinase 1δ-IN-6 | Casein Kinase | |
Casein kinase 1δ-IN-6 is a potent and selective inhibitor of the protein kinase CK-1δ with an IC50 of 23 nM.Casein kinase 1δ-IN-6 shows neuroprotective and anti-inflammatory activity in both in vitro and in vivo assays.C... |