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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9044 | SORT-PGRN interaction inhibitor 1 | Neurotensin Receptor | |
SORT-PGRN interaction inhibitor 1 is a potent sortilin-progranulin interaction inhibitor(IC50 of 2 μM). | |||
T3189 | B7/CD28 interaction inhibitor 1 | CTLA-4 inhibitor | Others |
B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) is a potent CTLA-4 inhibitor. | |||
T12351 | P53 and MDM2 proteins-interaction-inhibitor (racemic) | p53-and-mdm2-proteins-interaction-inhibitor-racemic | Others |
p53 and MDM2 proteins-interaction-inhibitor (racemic) is an inhibitor of the interaction between p53 and MDM2 proteins. | |||
T28219 | NusB-NusE interaction inhibitor-1 | ||
NusB-NusE interaction inhibitor-1 is a modulator of the NusB-NusE interaction. | |||
T12350 | P53 and MDM2 proteins-interaction-inhibitor dihydrochloride | Others | |
p53 and MDM2 proteins-interaction-inhibitor dihydrochloride is a interaction inhibitor between p53 and MDM2 proteins. | |||
T79106 | SORT-PGRN interaction inhibitor 3 | Neurotensin Receptor | |
SORT-PGRN Interaction Inhibitor 3 (Compound 13), with an IC50 value of 0.17 μM, acts as an inhibitor of the SORT-PGRN interaction, and is utilized in the study of neurodegenerative diseases [1]. | |||
T81126 | SORT-PGRN interaction inhibitor 2 | ||
SORT-PGRN Interaction Inhibitor 2 is a compound that downregulates SORT1 protein expression and enhances extracellular progranulin (PGRN) secretion in various mammalian cell lines, and is utilized in the study of neurolo... | |||
T82244 | HA-CD44 interaction inhibitor 2 | ||
Antitumor Agent-108 (Compound 5), an inhibitor of the Hyaluronic Acid (HA)-CD44 interaction, effectively disrupts cancer spheroid integrity and exhibits antiproliferative activity against cancer cells [1]. | |||
T79756 | Beclin1-ATG14L interaction inhibitor 1 | Autophagy | |
Beclin1-ATG14L Interaction Inhibitor 1 (COM 19) is a selective inhibitor targeting the specific interaction between Beclin1 and ATG14L. It impedes the formation of complex I in the lipid kinase VPS34, thus inhibiting aut... | |||
T82245 | HA-CD44 interaction inhibitor 1 | ||
Antitumor agent-109 (compound 6) is a dual-function inhibitor that targets hyaluronic acid and CD44, which are involved in tumor progression and invasion. It demonstrates potent antitumor activity, specifically inhibitin... | |||
T82902 | Beclin1-Bcl-2 interaction inhibitor 1 | ||
Beclin1-Bcl-2 Interaction Inhibitor 1 effectively disrupts the binding of Beclin 1 to Bcl-2, and is utilized in cancer and neurodegeneration research [1]. | |||
T3624 | A-366 | A 366,A366 | Epigenetic Reader Domain , Histone Methyltransferase |
A-366 is a highly selective peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP, respectively.It is more than 1,000-fold selective for G9a and GLP over the other 21 met... | |||
T5697 | BMS-1166 | PD-1/PD-L1 | |
BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor. | |||
T10860 | Col003 | HSP | |
Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM). It can be used for the investigation of fibrosis. | |||
T4647 | M2I-1 | M2I 1 | Others |
M2I-1 a small Mad2 inhibitor-1. the first small molecule inhibitor targeting the binding of Mad2 to Cdc20, an essential proteinprotein interaction (PPI) within the SAC. It can disturbs conformational dynamics of Mad2 cri... | |||
T8727 | TH1020 | TLR , Antibacterial | |
TH1020 is a novel Inhibitor of Toll-Like Receptor 5 (TLR5)/Flagellin Complex with promising activity (IC50 =0.85±0.12 μm) and specificity. | |||
T12979 | BI-3406 | p38 MAPK , MAPK , Ras | |
BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity. | |||
T11857 | LIT-001 | Oxytocin Receptor | |
LIT-001 improves social interaction in a mouse model of autism.It is the first nonpeptide oxytocin receptor agonist with EC50 of 55 nM and Ki of 226 nM. | |||
T9986 | (E/Z)-ZINC09659342 | Rho | |
(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction. | |||
T9461 | AZ194 | Sodium Channel | |
CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor. |