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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10511 | Anti-hypertensive sulfonanilide 1 | Others | |
Anti-hypertensive sulfonanilide 1 is an antihypertensive compound. | |||
T8158 | Tilianin | Others | |
Tilianin is a flavonoid glycoside of Dragocephalum moldavicum L. | |||
T3474 | RO 46-8443 | Endothelin Receptor | |
RO 46-8443 is the first non-peptide endothelin ETB receptor selective antagonist. RO 46-8443 displays up to 2000-fold selectivity for ETB receptors both in terms of binding inhibitory potency and functional inhibition. | |||
T0993 | Methoxamine hydrochloride | Methoxamine HCl | Adrenergic Receptor |
Methoxamine hydrochloride (Methoxamine HCl) is an alpha-1 adrenergic agonist that causes prolonged peripheral VASOCONSTRICTION. | |||
T22398 | Phenidone | 1-phenyl-3-pyrazolidinone | Lipoxygenase , COX |
Phenidone (1-phenyl-3-pyrazolidinone) is a dual inhibitor of cyclooxygenases and lipoxygenases that ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes[1]. The lipoxyg... | |||
T6S1369 | Vitexin | Apigenin-8-C-glucoside | Antioxidant |
1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can eit... | |||
T0287 | Hexamethonium Bromide | Gangliostat,Simpatoblock,Hexamethonium Dibromide | Apoptosis , Dopamine Receptor , AChR |
Hexamethonium Bromide (Hexamethonium Dibromide), a specific antagonist of neuronal-type nicotinic AChR in ganglia, is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. | |||
T28482 | Firibastat | QGC 001,QGC-001,RB-150,RB150,QGC001,RB 150 | Aminopeptidase |
Firibastat (RB150) is a glutamyl aminopeptidase antagonist and an orally active brain penetrating prodrug of EC33. It is a first-in-class brain aminopeptidase A (APA) inhibitor with a Ki of 200 nM. Firibastat selectively... | |||
T5329 | Trandolapril | Angiotensin-converting Enzyme (ACE) | |
Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat. | |||
T22236 | Alprenolol hydrochloride | 5-HT Receptor | |
Alprenolol hydrochloride is a non-selective blocker of beta, and also is a antagonist of5-HT1A receptor. | |||
T3046 | BMY 7378 dihydrochloride | BMY7378 HCl | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
BMY 7378 dihydrochloride (BMY7378 HCl) , α1D-adrenergic receptor antagonist, is a weak partial agonist/antagonist of 5-HT1A receptor. | |||
T9097 | Guanadrel | Others | |
Guanadrel is an antihypertensive agent. | |||
T1615 | Irbesartan | SR-47436,BMS-186295 | Apoptosis , RAAS |
Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist. | |||
T23044 | N,N'-Dicyclohexylurea | DCU,1,3-Dicyclohexylurea,NSC 17013,Dicyclohexylurea,Dicyclohexylcarbodiamide,AURORA KA-3582 | Epoxide Hydrolase |
N,N'-Dicyclohexylurea (AURORA KA-3582) is a soluble epoxide hydrolase (sEH) inhibitor. | |||
T6835 | Fenoldopam mesylate | Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526 | Dopamine Receptor |
Fenoldopam mesylate (Corlopam mesylate) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation. | |||
T80661 | Antihypertensive sulfonanilide XVII | Others | |
Antihypertensive sulfonanilide XVII is an orally available antihypertensive sulfonanilide small molecule compound for the study of hypertension. | |||
T79267 | Antihypertensive agent 3 | ||
Antihypertensive agent 3 (compound 4a), an angiotensin II receptor 1 antagonist, demonstrates antihypertensive activity in spontaneously hypertensive rats (SHRs) [1]. | |||
T79266 | Antihypertensive agent 2 | ||
Antihypertensive agent 2 (Compound 4g) exhibits effective antagonistic activities against angiotensin II receptor 1 and reduces blood pressure with equal or greater potency than Losartan [1]. | |||
T16329 | Nitroflurbiprofen | NO-flurbiprofen,Nitroxybutyl flurbiprofen,HCT 1206 | COX |
Nitroflurbiprofen (Nitroxybutyl flurbiprofen) is a NO-releasing COX inhibitor and modulates the increased intrahepatic vascular tone in portal hypertensive cirrhotic rats. | |||
T5581 | 6-(γ,γ-Dimethylallylamino)purine | N6-(2-lsopentenyl)adenine,Triacanthine | Others |
6-(γ,γ-Dimethylallylamino)purine (Triacanthine), which is a plant growth substance, shows hypertensive and antitumor activity, also cardiotonic, antispasmodic and a respiratory analeptic. |