generalized — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7061	Duloxetine		Serotonin Transporter
	Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder.		Serotonin Transporter
T1471	Duloxetine hydrochloride	Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl	Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine
	Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC and i...
T28270	Osemozotan HCl	Osemozotan hydrochloride,MN-305,MCI-242,MKC-242,MKC242,MCI242
	Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder.
T2132	Buspirone hydrochloride	Buspirone HCl,Narol,Buspar	Dopamine Receptor , 5-HT Receptor
	Buspirone hydrochloride (Buspar) is a 5HT(1A) receptor agonist, used to treat generalized anxiety disorder (GAD).		Dopamine Receptor , 5-HT Receptor
T7136	AZD-6280		GABA Receptor
	AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder.		GABA Receptor
T12156	N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea		Others
	N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea is an anticonvulsant agent, treatment of generalized tonic-clonic and partial seizures.		Others
T68058	Dulozafone	F1933	Others
	Dulozafone (F1933) has an anti- showed anticonvulsant activity in a brain amygdala ignition model and protected fully ignited rats from generalized seizures.		Others
T13569	Benin	Butocine,Butocin	Others
	Benin (Butocine) is an effective cytostatic drug used for the treatment of generalized carcinoma of the breast.		Others
T4762	L-Pipecolic acid	L-Homoproline,H-HoPro-OH	Endogenous Metabolite
	L-Pipecolic acid (L-Homoproline) is a breakdown product of lysine, accumulates in body fluids of infants with generalized genetic peroxisomal disorders, such as Zellweger syndrome, neonatal adrenoleukodystrophy.		Endogenous Metabolite
T8769	Harmaline hydrochloride	Harmidine hydrochloride	Others
	Harmaline hydrochloride (Harmidine hydrochloride) is a fluorescent indole alkaloid from the group of harmala alkaloids and beta-carbolines. It is the partially hydrogenated form of harmine.Harmaline produces a generalize...		Others
T1249	Beclamide	N-Benzyl-3-chloropropionamide,Chloracon,Chlorakon	Others
	Beclamide (Chlorakon) (N-benzyl-B-chloropropionamide) is a drug that possesses anticonvulsant activity. It is no longer used. It has been used as a sedative and as an anticonvulsant. It was studied in the 1950s for its a...		Others
T0675	Topiramate	RWJ 17021,McN 4853	Potassium Channel , Calcium Channel , GABA Receptor , Sodium Channel , GluR , Carbonic Anhydrase , iGluR
	Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepatic injury and largely when used in combination ...
T76778	Risankizumab	Risankizumab rzaa,SKYRIZI,ABBV 066,BI-655066	IL Receptor
	Risankizumab (BI 655066) is a humanized IgG monoclonal antibody (Kd <10 pM) targeting the IL-23 p19 subunit. Risankizumab inhibits IL-17 production induced by human IL-23 in mouse splenocytes with an IC50 value of 2 pM.R...		IL Receptor
T1885L	Siramesine Fumarate	LU-28179,LU-28-179,LU 28 179
	Siramesine Fumarate, a sigma receptor agonist, is used potentially for the treatment of generalized anxiety disorder.
T61376	Opipramol
	Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA) that primarily acts as a sigma (σ) receptor agonist, exhibiting potent interaction with sigma recognition sites (K i value of 50 nM). It can be employed i...
T11113	Duloxetine D3 hydrochloride	(S)-Duloxetine D3 hydrochloride,LY248686 D3 hydrochloride	Others
	Duloxetine D3 hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).Duloxetine D3 hydrochloride ...		Others
T14120	ACT-709478		Others
	ACT-709478 is a potent, selective T-type calcium channel blocker that is orally active and capable of penetrating the brain. It is currently utilized in research focusing on generalized epilepsies[1].		Others
T40910	Cognac oil
	Cognac oil, predominantly derived from wine lees, exhibits distinctive fatty acid compositions, characterized by high proportions of Palmitic acid (59.26%), Linoleic acid (11.92%), Myristic acid (8.97%), and Oleic acid (...
T68976	Piragliatin
	Piragliatin, also known as RO4389620, is a glucokinase activator. Piragliatin greatly enhances glucose-induced pancreatic islet respiration and insulin release. Piragliatin lowers plasma glucose both in the postabsorptiv...
T77032	Imsidolimab
	Imsidolimab (ANB 019), a high-affinity, humanized monoclonal antibody targeting IL-36R, antagonizes IL-36 cytokine signal transduction, showing potential in treating generalized pustular psoriasis (GPP) and other inflamm...