20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8134 | Cefathiamidine | Antibacterial , Antibiotic | |
Cefathiamidine exhibits a wide spectrum of antimicrobial activity against bacteria. Cefathiamidine is used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis | |||
T8345 | Carbutamide | Others | |
Carbutamide is a sulfonylurea antidiabetic agent with hypoglycemic activity. | |||
T15656 | KGA-2727 | SGLT | |
KGA-2727 is a potent and selective SGLT1 inhibitor, with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat). KGA... | |||
T6451 | Clodronic acid disodium salt | Loron,Clodronate Disodium,Lodronate | Others |
Clodronic acid disodium salt (Lodronate), a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption. | |||
T0370 | Pheniramine maleate | Daneral,Inhiston,Trimetose | 5-HT Receptor , Histamine Receptor |
Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived re... | |||
T0141 | Cephalonium | Cefalonium | Others |
Cephalonium (Cefalonium) is a first-generation cephalosporin antibiotic. | |||
TP1419L | HAEGTFT acetate(926018-95-3 free base) | Glucagon Receptor | |
HAEGTFT acetate is the first N-terminal 1-7 residues of GLP-1 peptide. | |||
TP1381L | HAEGT TFA(852155-81-8 free base) | Others | |
HAEGT TFA is the first N-terminal 1-5 residues of GLP-1 peptide. | |||
T8063 | Cephapirin Benzathine | Others , Antibacterial , Antibiotic | |
Cephapirin Benzathine is a semisynthetic, broad-spectrum, first-generation cephalosporin with antibacterial activity. | |||
T0803 | Acetrizoic acid | Urokon,Opacaron,Acetrizoesaeure | Others |
Acetrizoic acid (Urokon) is the first monomeric ionic compound used as an X-ray contrast agent. | |||
T4584 | BMS-813160 | BMS 813160 | CCR |
BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular. | |||
T2733 | Sarsasapogenin | Parigenin,Sarsagenin | Apoptosis , NF-κB , Endogenous Metabolite |
Sarsasapogenin (Parigenin) is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin. It is named after sarsaparilla (Smilax sp.), a family of climbing plants found in subtropical regions. It was one o... | |||
T26195 | SMI481 | NPPM-6748-481,NPPM 6748-481,NPPM6748481,SMI-481 SMI 481,NPPM 6748481 | Others |
SMI481 (NPPM6748481) is the first small-molecule Sec14-like phosphatidylinositol transfer proteins (PITPs) inhibitor. | |||
T9901 | Adalimumab | TNF | |
Adalimumab (anti-TNF-alpha) is the first fully human recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha. | |||
T5763 | Sedanolide | Others , Autophagy | |
Sedanolide is a natural phthalide first isolated from seed oil of the Umbelliferae family, including celery. | |||
T6859 | I-BRD9 | GSK602 | Epigenetic Reader Domain |
I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3. | |||
T4S0647 | Butylphthalide | 3-Butylphthalide,3-n-Butylphathlide,3-n-Butylphthalide | Others |
Butylphthalide (3-Butylphthalide) is an anti-cerebral-ischemia drug; first isolated from the seeds of Apium graveolens Linn. | |||
T14547 | JWG-071 | JWG071,JWG 071 | ERK , Epigenetic Reader Domain |
JWG-071, the first reported chemical probe for ERK5 kinase selectivity, is a BET-selective inhibitor with a 1 μM BRD4 IC that enhances both ERK5 activity and BRD4 selectivity. | |||
T8374 | LJ570 | PPAR | |
LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[) | |||
TP1382L | HAEGTFTSDVS acetate | HAEGTFTSDVS acetate(864915-61-7 free base) | Glucagon Receptor |
HAEGTFTSDVS acetate is the first N-terminal 1-11 residues of GLP-1 which stimulates insulin secretion from pancreatic β-cells. |