elimination — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7100	PLX5622	PLX-5622	c-Fms , CSF-1R
	PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor.		c-Fms , CSF-1R
T4989	Fosfomycin Tromethamine		Antibacterial , Antibiotic
	An antibiotic produced by Streptomyces fradiae.		Antibacterial , Antibiotic
T3131	Fosfomycin calcium	Phosphomycin calcium salt,Fosmicin	Antibacterial , Antibiotic
	Fosfomycin calcium (Phosphomycin calcium salt) is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis.		Antibacterial , Antibiotic
T8262	Fosfomycin sodium	Fosfomycin Disodium	Antibacterial , Antibiotic
	Fosfomycin sodium is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by irreversibly inhibiting an e...		Antibacterial , Antibiotic
T3875	CLINODISIDE A		Others
	Clinodiside A in rats with one compartment open model into the body, rapid distribution, elimination rate.		Others
T15251	Etebenecid	Urelim	Others
	Etebenecid (Urelim) is uricosuric agents, which lower uric acid levels in the body by increasing the elimination of uric acid by the kidneys. It also inhibits penicillin tubular secretion.		Others
T62525	TP-16		Prostaglandin Receptor
	TP-16 is a novel potent and selective EP4 antagonist that blocks the function of IMCs and enhances cytotoxic T cell-mediated tumor elimination in vivo.		Prostaglandin Receptor
T15604	IU1-47		DUB
	IU1-47 is an effective and specific USP14 inhibitor (IC50: 0.6 μM). IU1-47 causes tau elimination in cultured neurons. IU1-47 inhibits IsoT/USP5 (IC50: 20 μM).		DUB
T6397	Atracurium besylate	Tracrium,51W89,BW-33A	AChR
	Atracurium besylate (51W89) is a non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for eliminat...		AChR
T5068	D-Glucuronic acid sodium salt monohydrate	Sodium D-glucuronate,D(+)-Glucuronic acid sodium salt monohydrate	Others , Endogenous Metabolite
	D-Glucuronic acid sodium salt monohydrate (Sodium D-glucuronate) is a carboxylic acid and highly soluble in water. In humans, glucuronic acid is often linked to toxic or poisonous substances to allow for subsequent elimi...		Others , Endogenous Metabolite
T72028	2-Quinolinecarboxaldehyde	Quinoline-2-carbaldehyde
	2-Quinolinecarboxaldehyde (Quinoline-2-carbaldehyde) is a small rigid molecule that is a compound in the Henry reaction and subsequent elimination. 2-Quinolinecarboxaldehyde inhibits AChE with an IC50 of 13.48 μM.
T8073	Disodium succinate	Sodium succinate	Others
	Disodium succinate (Sodium succinate) is the sodium salt form of succinate, which is an important metabolite at the cross-road of several metabolic pathways and involved in the formation and elimination of reactive oxyge...		Others
T0195	Secnidazole	RP-14539,PM-185184	Antibiotic , Parasite
	Secnidazole (PM-185184) is a second-generation 5-nitroimidazole antimicrobial that is structurally related to other 5-nitroimidazoles including [DB00916] and [DB00911], but displays improved oral absorption and longer te...		Antibiotic , Parasite
T5117	Hexaflumuron		Others
	Hexaflumuron is a chitin synthesis inhibitor used to bait and eliminate termite colonies. Termites are unable to metabolize hexaflumuron and clearance is slow, resulting in up to 100% elimination. Hexaflumuron has also b...		Others
T40795	BNTA		Reactive Oxygen Species
	BNTA is a potent extracellular matrix (ECM) modulator. In a rat model of arthritis, BNTA modulates arthritis by promoting the synthesis of cartilage structural molecules on chondrocytes through the induction of superoxid...		Reactive Oxygen Species
T8947	Dasiglucagon acetate	dasiglucagon acetate(1544300-84-6 free base)	Others
	Dasiglucagon acetate is a novel glucagon analog for diabetic hypoglycemia therapy. Dasiglucagon acetate has demonstrated established solubility and stability in an aqueous formulation. Pharmacokinetics studies have shown...		Others
T0153	Oltipraz	NSC 347901,RP 35972	HIF/HIF Prolyl-Hydroxylase , HIV Protease , Reverse Transcriptase , Nrf2 , HIF
	Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties. Oltipraz induces phase II detoxification enzymes, such as glutathione S transferase (GST) and NAD(P)H: quin...
T3779	Crocin II	Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B	Caspase , COX , NO Synthase
	Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expres...		Caspase , COX , NO Synthase
T29075	UR-7247	UR7247
	UR-7247 is an angiotensin type 1 receptor antagonist with a very long plasma elimination half-life.
T33291	Meproscillarin	KY-18,Rambufaside,Clift,KY 18,KY18
	Meproscillarin is a glycoside with high bioavailability (about 70%) and an elimination independent of renal function.