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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4197 | HZ-1157 | HZ1157,DHFR-inhibitor | HCV Protease |
HZ-1157 (DHFR-inhibitor) is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV NS3/4A protease. | |||
T9618 | HeE1-2Tyr | SARS-CoV | |
HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor. It significantly inhibits West Nile, Dengue and SARS-CoV-2 RdRps (IC50 of 27.6 µM) activity in vitro. | |||
T23004 | ML-SA1 | Mucolipin synthetic agonist 1 | Others , TRP/TRPV Channel |
ML-SA1 (Mucolipin synthetic agonist 1) is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 value of ML-SA1 against DENV... | |||
T11760 | KIN101 | 3-(4-Bromophenyl)-7-[(methylsulfonyl)oxy]-4-oxo-4H-chromene | HCV Protease , Influenza Virus , RSV , Antifection |
KIN101 (3-(4-Bromophenyl)-7-[(methylsulfonyl)oxy]-4-oxo-4H-chromene), an isoflavone agonist of IRF-3 dependent signaling, induces IRF-3 nuclear translocation. KIN101 has antiviral activity against RNA viruses, HCV, and R... | |||
T13397 | ZINC03129319 | Virus Protease | |
ZINC03129319 is an inhibitor of dengue virus (DENV) NS2B-NS3 protease. | |||
T8886 | NITD-2 | DNA/RNA Synthesis | |
NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly. Dengue virus (DENV) is the most prevalent mosquito- borne viral pathogen in hu... | |||
T64091 | (-)-JNJ-A07 | Others | |
(-)-JNJ-A07 is a selective and potent dengue virus (DENV) inhibitor (EC50:31 nM) with antiviral activity for the study of dengue virus infections. | |||
T16914 | SP187 | UV4,MON-DNJ | Others , Virus Protease , Influenza Virus |
SP187 (MON-DNJ) is a host-targeted iminosugar. It has anti-filovirus infection activity.SP187 is used for therapeutic use against influenza and dengue viruses. | |||
TN2027 | Oxysanguinarine | 8-Oxosanguinarine,Hydroxysanguinarine | Parasite |
Oxysanguinarine (Hydroxysanguinarine) possesses antiplatelet aggregation activity, it has potential inhibitory properties against the dengue virus. | |||
T16325 | NITD008 | 7-Deaza-2'-C-acetylene-adenosine | Others |
NITD008 (7-Deaza-2'-C-acetylene-adenosine) is a potent and selective adenosine nucleoside inhibitor.NITD008 is an adenosine nucleoside analog with broad-spectrum antiviral activity that inhibits dengue, animal cupripoxvi... | |||
T63143 | DENV-IN-5 | Virus Protease , HIV Protease | |
Denv-in-5 is an effective and selective dengue virus (DENV) inhibitor with EC50 values of 1.47, 9.23, 7.08, 8.91 μM for denV-I-IV and 0.1512 μM for HIV-1IIIB. | |||
T17190 | U18666A | Others , HCV Protease | |
U18666A is a cell-permeable drug and is a cholesterol synthesis and transport inhibitor. It inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus. | |||
T16702 | QL47 | Virus Protease , BTK | |
QL47 is a host-targeted small molecule antiviral agent with antiviral activity against dengue and other RNA viruses.QL47 acts as an inhibitor of viral translation and a covalent inhibitor of BTK, and can be used in the s... | |||
T38960 | QL-X-138 | Virus Protease , MNK , BTK | |
QL-X-138 is a potent and selective BTK and MNK dual kinase inhibitor that binds covalently to BTK and non-covalently to MNK.The IC 50 s of QL-X-138 against BTK, MNK1 and MNK2 kinases are 9.4 nM, 107.4 nM and 26 nM, respe... | |||
T76856 | Andecaliximab | GS-5745 | MMP , Virus Protease |
Andecaliximab is a recombinant IgG4 monoclonal antibody targeting matrix metalloproteinase 9 (MMP9). Andecaliximab showed antifibrotic effects in a mouse model of idiopathic pulmonary fibrosis. Andecaliximab can be used ... | |||
TN1065 | Hirsutine | Apoptosis | |
Hirsutine induces apoptosis and is a potent Dengue virus inhibitor exhibiting low cytotoxicity.Hirsutine has anticancer, cardioprotective, anti-hypertensive and anti-arrhythmic activities, it also has vasodilatation acti... | |||
T11281L | FGI-106 tetrahydrochloride | Virus Protease , HCV Protease , Influenza Virus , HIV Protease | |
FGI-106 tetrahydrochloride demonstrates potent inhibitory activity across a broad spectrum of viruses, including those causing hemorrhagic fevers such as Ebola, Rift Valley, and Dengue Fever, with half-maximal effective ... | |||
T38960L | QL-X-138 HCl | QL-X-138 HCl(1469988-63-3 Free base) | MNK , BTK |
QL-X-138 HCl is a novel selective and highly potent BTK/MNK dual-kinase inhibitor with anticancer activity that binds covalently to BTK and noncovalently to MNK. QL-X-138 HCl inhibited BTK, MNK1, and MNK2 kinases. QL-X-1... | |||
T24432 | MB21 | MB-21,MB 21 | |
MB21 is a dengue type 2 protease inhibitor that acts by inhibiting each one of the four serotypes of dengue viruses in infected cells in culture. | |||
T69649 | NITD-688 | ||
NITD-688 is a pan-serotype inhibitor targeting the dengue virus NS4B protein, effective through oral administration. It holds potential in dengue virus (DENV) research applications. |