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KIN101

Catalog No. T11760 CAS 610753-87-2

Synonyms: 3-(4-Bromophenyl)-7-[(methylsulfonyl)oxy]-4-oxo-4H-chromene

KIN101, an isoflavone agonist of IRF-3 dependent signaling, induces IRF-3 nuclear translocation. KIN101 has antiviral activity against RNA viruses, HCV, and RSV.

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KIN101, CAS 610753-87-2

Pack Size	Availability	Price/USD
5 mg	In stock	59.00
10 mg	In stock	86.00
25 mg	In stock	157.00
50 mg	In stock	239.00
100 mg	In stock	356.00
200 mg	In stock	534.00
500 mg	In stock	797.00
1 mL * 10 mM (in DMSO)	In stock	69.00

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Purity 99.46%

HNMR HPLC COA

Datasheet SDS

Biological Description

Chemical Properties

Storage & Solubility Information

Description	KIN101, an isoflavone agonist of IRF-3 dependent signaling, induces IRF-3 nuclear translocation. KIN101 has antiviral activity against RNA viruses, HCV, and RSV.
Targets&IC50	influenza virus , DNV

Synonyms	3-(4-Bromophenyl)-7-[(methylsulfonyl)oxy]-4-oxo-4H-chromene
Purity	99.46%
Molecular Weight	395.23
Formula	C16H11BrO5S
CAS No.	610753-87-2

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 6 months

Solubility Information

DMSO: 32 mg/mL (80.97 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Bedard KM, et al. Isoflavone agonists of IRF-3 dependent signaling have antiviral activity against RNA viruses. J Virol. 2012 Jul;86(13):7334-44. 2. Shawn P. Iadonato, et al. Anti-viral compounds, pharmaceutical compositions and methods of use thereof. US20160122312A1.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.