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HZ-1157

HZ-1157
HZ-1157 (DHFR-inhibitor) is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV NS3/4A protease.
Catalog No. T4197Cas No. 1009734-33-1
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Purity:98.23%
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HZ-1157

Catalog No. T4197Cas No. 1009734-33-1
HZ-1157 (DHFR-inhibitor) is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV NS3/4A protease.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$31In Stock
2 mg$44In Stock
5 mg$68In Stock
10 mg$109In Stock
25 mg$207In Stock
50 mg$328In Stock
100 mg$531In Stock
1 mL x 10 mM (in DMSO)$82In Stock
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Product Introduction

Bioactivity
Description
HZ-1157 (DHFR-inhibitor) is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV NS3/4A protease.
Targets&IC50
HCV NS3/4A protease:1.0 μmol/L (IC50)
AliasHZ1157, DHFR-inhibitor
Chemical Properties
Molecular Weight232.28
FormulaC12H16N4O
Cas No.1009734-33-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 10 mg/mL (43.05 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.3051 mL21.5257 mL43.0515 mL215.2574 mL
5 mM0.8610 mL4.3051 mL8.6103 mL43.0515 mL
10 mM0.4305 mL2.1526 mL4.3051 mL21.5257 mL
20 mM0.2153 mL1.0763 mL2.1526 mL10.7629 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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