collagen — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10861	Collagen proline hydroxylase inhibitor-1		Others
	Collagen proline hydroxylase inhibitor-1 exhibits antifibroproliferative activity.		Others
T80025	Bovine Type II Collagen	Collagen, Type II, Immunization Grade
	Type II collagen is a protein that demonstrates considerable effectiveness in alleviating pain and inflammation associated with collagen-induced arthritis in mice, with notable application in the treatment of osteoarthri...
T10862	Collagen proline hydroxylase inhibitor		Others
	Collagen proline hydroxylase inhibitor is an inhibitor collagen proline hydroxylase and useful for antifibrotic proliferative agents.		Others
TP2301	Type II collagen fragment		Others
	Type II collagen is composed of a triple helix of three identical α chains. These molecules associate to form a fibril that is stabilized by intermolecular crosslinks1. Damage to the fibrillar meshwork, made up of primar...		Others
TP1643	Alpha 1(I) Collagen (614-639), human
	This is a peptide inhibitor of collagen fibrillar matrix assembly.
TP2452	Collagen type IV alpha1 (531-543)	Hep III peptide,Gefyfdlrlkgdk
	Collagen type IV alpha1 (531-543) is a protein that in humans is encoded by the COL4A1 gene on chromosome 13. It is ubiquitously expressed in many tissues and cell types. COL4A1 is a subunit of type IV collagen and plays...
T60303	Collagen-IN-1
	Collagen-IN-1 (compound 3) is an ortho-carbonyl hydroquinone derivative exhibiting selective inhibition of collagen. It non-competitively inhibits agonist-induced platelet aggregation, with an IC50 value of 1.77 μM. Coll...
T7692	2,4-DPD		HIF
	2,4-DPD is competitive inhibitor of the oxygen-sensing enzyme HIF-α prolyl hydroxylase (HIF-PH)		HIF
T2057	BVT 2733		Dehydrogenase
	BVT 2733 is a new, non-steroidal, isoform-specific inhibitor of 11β-HSD1.		Dehydrogenase
T37512	Cis-4-Hydroxy-L-proline		Endogenous Metabolite
	cis-L-Hydroxyproline inhibits the synthesis and extracellular deposition of collagen. The growth inhibition of pancreatic cancer cells induced by the Hyp isomer could be due to endoplasmatic reticulum stress.		Endogenous Metabolite
T10860	Col003		HSP
	Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM). It can be used for the investigation of fibrosis.		HSP
T16886	Sinefungin	Adenosyl-Ornithine,A-9145,Antibiotic 32232RP	Others , Histone Methyltransferase , Antibiotic , Antifungal
	Sinefungin (Adenosyl-Ornithine) is an effective inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. Sinefungin is a SET7/9 inhibitor and ameliorates r...
TP1328	TB500		Others
	TB-500 is a synthesised peptide, essentially a short-chain version of the naturally occurring Thymosin Beta-4.		Others
T21616	L-006235	L 006235	Cysteine Protease
	L-006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM.		Cysteine Protease
T11699	J-113863		CCR
	J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptor...		CCR
T6856	Halofuginone	Tempostatin,empostatin,RU-19110	Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
	Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal.
T4283	SRI-011381		TGF-beta/Smad
	SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.		TGF-beta/Smad
T3524	Halofuginone hydrobromide	Tempostatin,RU-19110 (hydrobromide),Stenorol	Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
	Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce...
T9195	SHR0302	ARQ252	Apoptosis , JAK
	SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3, 420 times for Tyk2).		Apoptosis , JAK
T6576	Malotilate	Malotilatum,NKK 105,Kantec	Lipoxygenase
	Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.		Lipoxygenase