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Search Results for " cognitive-enhancing "

13

Compounds

Cat No. Product Name Synonyms Targets
T3026 (-)-Huperzine A HupA,Huperzine A Apoptosis , AChR , AChE , iGluR
(-)-Huperzine A (HupA) , an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the tr...
T7829 FK962 Somatostatin
FK962 is an somatostatin release enhancer , exerts cognitive-enhancing actions.
T16816 S 18986 GluR
S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, showcasing cognitive-enhancing properties in rodents. It induces the release of noradrenaline and acetylcholine...
T28655 Sabeluzole R 58735,R58735,R-58735 Microtubule Associated
Sabeluzole (R-58735) has antiepileptic and cognitive enhancing effects, inhibits neurotoxin-induced tau expression and cell death.Sabeluzole is protective against chlordiazepoxide-induced habituation disorders and may be...
T27806 Lecozotan HCl SRA-333,SRA333,SRA 333,Lecozotan hydrochloride 5-HT Receptor
Lecozotan HCl (SRA-333) is a potent and selective 5-HT antagonist that significantly enhances KCl-stimulated glutamate and acetylcholine release from the hippocampal dentate gyrus and has cognitive enhancing properties. ...
T0869 Atomoxetine hydrochloride Tomoxetine hydrochloride,(R)-Tomoxetine hydrochloride,LY 139603,Atomoxetine HCl,LY 139603 HCl Dopamine Receptor , 5-HT Receptor , Norepinephrine
Atomoxetine hydrochloride (LY 139603) is the hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine reuptake inhibitor with cognitive-enhancing activity. Althou...
T15758 Linopirdine DuP 996 Potassium Channel , TRP/TRPV Channel
Linopirdine (DuP 996) is a TRPV1 agonist. Linopirdine is an orally active and selective M-type K+ current (IM; Kv7; KCNQ Channels) inhibitor (IC50: 2.4 μM). Linopirdine is a cognitive enhancer. It acts by stimulating rel...
T32191 Irdabisant CEP-26401,CEP 26401,CEP26401 Histamine Receptor
Irdabisant (CEP-26401) (CEP-26401) is a selective, orally active and blood-brain barrier (BBB) penetrant antagonist/inverse agonist of histamine H3 receptor (H3R) (rat H3R Ki= 7.2 nM, human H3R Ki= 2.0 nM). Irdabisant ex...
T2563 Acetyl-L-carnitine hydrochloride Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride Others , Endogenous Metabolite
Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) is a nutritional supplement composed of the hydrochloride salt form of the acetylated form of the endogenously produced L-carnitine, with potential neur...
T70715 AQW-051 fumarate
AQW-051 fumarate is an α7 nicotinic ACh receptor partial agonist that may act as a cognitive-enhancing agent.
T27326 FK960 FK 59960,FK-960,FK-59960,FK59960
FK962 is an enhancer of somatostatin release, which exerts cognitive-enhancing actions in rats. FK960 increases synaptic density in the hippocampal CA3 region of aged rats.
T27379 FR-194921 FR194921
FR-194921 is a potent, selective, and orally active antagonist for central adenosine A1 receptors with cognitive-enhancing and anxiolytic activity. FR194921 has same binding affinity profile among human, rat, and mouse.
T10224 ABT-418 hydrochloride Others
ABT-418 hydrochloride is a selective agonist of nAChRs with cognitive enhancing and anxiolytic activities. It activates cholinergic channel and can be used for the research of Alzheimer's disease.
TargetMol