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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3026 | (-)-Huperzine A | HupA,Huperzine A | Apoptosis , AChR , AChE , iGluR |
(-)-Huperzine A (HupA) , an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the tr... | |||
T7829 | FK962 | Somatostatin | |
FK962 is an somatostatin release enhancer , exerts cognitive-enhancing actions. | |||
T16816 | S 18986 | GluR | |
S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, showcasing cognitive-enhancing properties in rodents. It induces the release of noradrenaline and acetylcholine... | |||
T28655 | Sabeluzole | R 58735,R58735,R-58735 | Microtubule Associated |
Sabeluzole (R-58735) has antiepileptic and cognitive enhancing effects, inhibits neurotoxin-induced tau expression and cell death.Sabeluzole is protective against chlordiazepoxide-induced habituation disorders and may be... | |||
T27806 | Lecozotan HCl | SRA-333,SRA333,SRA 333,Lecozotan hydrochloride | 5-HT Receptor |
Lecozotan HCl (SRA-333) is a potent and selective 5-HT antagonist that significantly enhances KCl-stimulated glutamate and acetylcholine release from the hippocampal dentate gyrus and has cognitive enhancing properties. ... | |||
T0869 | Atomoxetine hydrochloride | Tomoxetine hydrochloride,(R)-Tomoxetine hydrochloride,LY 139603,Atomoxetine HCl,LY 139603 HCl | Dopamine Receptor , 5-HT Receptor , Norepinephrine |
Atomoxetine hydrochloride (LY 139603) is the hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine reuptake inhibitor with cognitive-enhancing activity. Althou... | |||
T15758 | Linopirdine | DuP 996 | Potassium Channel , TRP/TRPV Channel |
Linopirdine (DuP 996) is a TRPV1 agonist. Linopirdine is an orally active and selective M-type K+ current (IM; Kv7; KCNQ Channels) inhibitor (IC50: 2.4 μM). Linopirdine is a cognitive enhancer. It acts by stimulating rel... | |||
T32191 | Irdabisant | CEP-26401,CEP 26401,CEP26401 | Histamine Receptor |
Irdabisant (CEP-26401) (CEP-26401) is a selective, orally active and blood-brain barrier (BBB) penetrant antagonist/inverse agonist of histamine H3 receptor (H3R) (rat H3R Ki= 7.2 nM, human H3R Ki= 2.0 nM). Irdabisant ex... | |||
T2563 | Acetyl-L-carnitine hydrochloride | Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride | Others , Endogenous Metabolite |
Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) is a nutritional supplement composed of the hydrochloride salt form of the acetylated form of the endogenously produced L-carnitine, with potential neur... | |||
T70715 | AQW-051 fumarate | ||
AQW-051 fumarate is an α7 nicotinic ACh receptor partial agonist that may act as a cognitive-enhancing agent. | |||
T27326 | FK960 | FK 59960,FK-960,FK-59960,FK59960 | |
FK962 is an enhancer of somatostatin release, which exerts cognitive-enhancing actions in rats. FK960 increases synaptic density in the hippocampal CA3 region of aged rats. | |||
T27379 | FR-194921 | FR194921 | |
FR-194921 is a potent, selective, and orally active antagonist for central adenosine A1 receptors with cognitive-enhancing and anxiolytic activity. FR194921 has same binding affinity profile among human, rat, and mouse. | |||
T10224 | ABT-418 hydrochloride | Others | |
ABT-418 hydrochloride is a selective agonist of nAChRs with cognitive enhancing and anxiolytic activities. It activates cholinergic channel and can be used for the research of Alzheimer's disease. |