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Acetyl-L-carnitine hydrochloride

Catalog No. T2563 CAS 5080-50-2

Synonyms: Acetyl L-carnitine hydrochloride, O-Acetylcarnitine, O-acetyl-L-carnitine, O-Acetyl-L-carnitine hydrochloride

Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) is a nutritional supplement composed of the hydrochloride salt form of the acetylated form of the endogenously produced L-carnitine, with potential neuroprotective, cognitive-enhancing, anti-depressive and immunomodulating activities. It may also relieve peripheral neuropathy induced by chemotherapy, diabetes or other diseases. In addition, acetyl-L-carnitine may modulate the immune response by increasing T-lymphocytes maturation and may downregulate pro-inflammatory cytokines in response to viruses, such as SARS-CoV-2. It may also disrupt the ACE2 signaling pathway and inhibit the production of reactive oxygen species (ROS).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Acetyl-L-carnitine hydrochloride Chemical Structure

Acetyl-L-carnitine hydrochloride, CAS 5080-50-2

Pack Size	Availability	Price/USD
10 mg	In stock	$ 36.00
25 mg	In stock	$ 58.00
50 mg	In stock	$ 84.00
100 mg	In stock	$ 112.00
200 mg	In stock	$ 143.00
500 mg	In stock	$ 243.00
1 mL * 10 mM (in DMSO)	In stock	$ 94.00

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Purity: 98.81%

Purity: 96.99%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Acetyl L-carnitine hydrochloride, O-Acetylcarnitine, O-acetyl-L-carnitine, O-Acetyl-L-carnitine hydrochloride
Molecular Weight	239.7
Formula	C9H18ClNO4
CAS No.	5080-50-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 30 mg/mL (125.16 mM)

References and Literature

1. Stephens, F., Constantin-Teodosiu, D., & Greenhaff, P. (2007). New insights concerning the role of carnitine in the regulation of fuel metabolism in skeletal muscle. The Journal Of Physiology, 581(2), 431-444. doi: 10.1113/jphysiol.2006.125799 2. Wang, S., Han, C., Lee, S., Patkar, A., Masand, P., & Pae, C. (2014). A review of current evidence for acetyl-l-carnitine in the treatment of depression. Journal Of Psychiatric Research, 53, 30-37. doi: 10.12016/j.jpsychires.2014.02.2005 3. Cuccurazzu, B., Bortolotto, V., Valente, M., Ubezio, F., Koverech, A., Canonico, P., & Grilli, M. (2013). Upregulation of mGlu2 Receptors via NF-κB p65 Acetylation Is Involved in the Proneurogenic and Antidepressant Effects of Acetyl-L-Carnitine. Neuropsychopharmacology, 38(11), 2220-2230. doi: 10.1038/npp.2013.121

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Human Endogenous Metabolite Library Anti-Obesity Compound Library Clinical Compound Library RO5 Drug-like Natural Product Library Human Metabolite Library Bioactive Compound Library Human Endogenous Metabolite Compound Library Plus FDA-Approved & Pharmacopeia Drug Library Bioactive Lipid Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

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