canine — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1098	Motilin, canine	Motilin (canine)
	Motilin canine, a 22-amino acid peptide, functions as a robust gastrointestinal smooth muscle contraction agonist.
TP1085L	Neuromedin N acetate(92169-45-4 free base)	Neuromedin N (rat, mouse, porcine, canine) acetate	Dopamine Receptor
	Neuromedin N acetate(92169-45-4 free base) is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.Neuromedin N is a potent modulator of d...		Dopamine Receptor
TP1610	Secretin, canine
	Secretin is an endocrine hormone that stimulates the secretion of bicarbonate-rich pancreatic fluids. Canine secretin can regulates gastric chief cell function and paracellular permeability in canine gastric monolayers b...
TP1174	Endothelin-2 (49-69), human	Human endothelin-2,Endothelin-2, human,Endothelin-2 (human, canine)	Others
	Endothelin-2 (49-69), human (Human endothelin-2) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.		Others
TP1085	Neuromedin N	Neuromedin N (rat, mouse, porcine, canine)
	Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.
TP1016	Aviptadil	Vasoactive Intestinal Peptide (human, rat, mouse, rabbit, canine, porcine)
	Aviptadil (INN) is an analog of vasoactive intestinal polypeptide (VIP) for the treatment of erectile dysfunction.
T80148	GRP (14-27) (human, porcine, canine)		Bombesin Receptor
	GRP (14-27) (human, porcine, canine) functions as a ligand for bombesin receptors, with its specific binding being inhibited by GTP and GDP, while GMP does not affect it [1].		Bombesin Receptor
TP2143	Endothelin-2 (49-69), human TFA	Endothelin-2 (49-69) (human, canine) TFA,Human endothelin-2 TFA	Others
	Endothelin-2 (49-69), human (TFA) is a 21-amino acid vasoactive peptide that binds to ET-RA and ET-RB.		Others
T16347	NS3623		Potassium Channel
	NS3623 is an activator of human ether-a-go-go-related gene potassium channels. NS3623 has a dual mode of action, being an inhibitor of hERG1 channels. NS3623 activates the IKr and Ito currents and has an antiarrhythmic e...		Potassium Channel
T76651	Peptide YY (13-36) (canine, mouse, porcine, rat)
	Peptide YY (13-36) (canine, mouse, porcine, rat) is a Y 2 receptor subtype agonist [1] .
T0696	Naftopidil	KT-611,BM-15275	Adrenergic Receptor
	Naftopidil (KT-611) (INN, marketed under the brand name Flivas), an antihypertensive medicine, is used as a selective α1-adrenergic receptor antagonist or α-blocker.		Adrenergic Receptor
T6600	Naftopidil dihydrochloride	KT-611,KT-611 2HCl,Naftopidil DiHCl	5-HT Receptor , Adrenergic Receptor
	Naftopidil dihydrochloride (KT-611 2HCl) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.		5-HT Receptor , Adrenergic Receptor
T8236	RHC 80267	U-57908	Others , Phospholipase , COX , Acyltransferase , AChR
	RHC 80267 (U-57908) is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)		Others , Phospholipase , COX , Acyltransferase , AChR
TP1016L	Aviptadil Acetate	Vasoactive Intestinal Peptide acetate salt	RAAS , SARS-CoV
	Aviptadil Acetate (Vasoactive Intestinal Peptide acetate salt) induces pulmonary vasodilation and inhibits the proliferation of vascular SMCs and platelet aggregation. Avitadil acetate can be used for research on pulmona...		RAAS , SARS-CoV
T9220	Naftopidil hydrochloride	1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-,KT-611 hydrochloride,BM-15275 hydrochloride	Adrenergic Receptor
	Naftopidil hydrochloride (BM-15275 hydrochloride) is a selective alpha1-adrenoceptor antagonist with Ki of 3.7 nM, 20 nM and 1.2 nM for the cloned human α1a-adrenoceptor, α1b-adrenoceptor and α1d-adrenoceptor, respective...		Adrenergic Receptor
TN5768	Chiricanine A
	Chiricanine A is a natural product for research related to life sciences. The catalog number is TN5768 and the CAS number is 350593-30-5.
TN1485	Chicanine		Others , NF-κB , Prostaglandin Receptor
	Chicanine has anti-inflammatory activity in macrophages by down-regulating LPS-induced inflammatory cytokines in IκBα±/MAPK/ERK signaling pathways.		Others , NF-κB , Prostaglandin Receptor
T15209	Elobixibat	AZD 7806,A 3309	Others
	Elobixibat (A 3309) is an inhibitor of the ileal bile acid transporter (IC50: 0.13 nM, 0.53 nM, and 5.8 nM for mouse, human, and canine IBAT). Elobixibat can be used in studies about chronic idiopathic constipation.		Others
T22893	L-168049	L-168,049	Glucagon Receptor
	L-168049 is a selective and non-competitive antagonist of human glucagon receptor with IC50s of 3.7 nM, 63 nM, and 60 nM for human, murine, and canine, respectively.		Glucagon Receptor
T28895	T-0509	T 0509,T0509	Adrenergic Receptor
	T-0509 is a selective beta 1 receptor agonist that increases inotropy in canine ventricular muscle and selectively down-regulates rat cardiac beta 1-adrenoceptors.		Adrenergic Receptor