bfgf — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T82890	bFGF (119-126)
	bFGF (119-126) is a biologically active peptide corresponding to the residues of human, bovine (119-126), mouse, rat (118-125), and Heparin-Binding Growth Factor 2 (118-125) within bFGF. It functions to inhibit the dimer...
T1843	XMD8-92		ERK , BMI-1 , Epigenetic Reader Domain
	XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).		ERK , BMI-1 , Epigenetic Reader Domain
T3714	SUN11602	SUN 11602	ERK , FGFR
	SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor. It mimics the neuroprotective effects of bFGF and prevents glutamate-induced neuronal death. It also increases level...		ERK , FGFR
T10870L	CP-547632		VEGFR , FGFR , PDGFR , BTK
	CP-547632 is an orally available and potent, ATP-competitive dual inhibitor of VEGFR-2 and FGF kinase F with IC50s of 11 nM and 9 nM, respectively. CP-547632 is selective, with higher selectivity for VEGFR2 and bFGF than...		VEGFR , FGFR , PDGFR , BTK
T5S1103	Isoliensinine	Isoliensinin	Apoptosis , Antioxidant
	1. Isoliensinine (Isoliensinin), a natural phenolic bisbenzyltetrahydroisoquinoline alkaloid, has received considerable attention for its potential biological effects such as antioxidant and anti-HIV activities. 2. Isoli...		Apoptosis , Antioxidant
T2787	Picroside I	6'-Cinnamoylcatalpol	MMP , STAT
	Picroside I (6'-Cinnamoylcatalpol), a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B. It has antioxidant, and anti-inflammatory activities, it may be the valuable anti-invasive drug ...		MMP , STAT
T2160	Suramin Sodium Salt	BAY-205,Suramin hexasodium salt,NF-060	Apoptosis , Phosphatase , SARS-CoV , Sirtuin , Reverse Transcriptase , Topoisomerase , Parasite
	Suramin Sodium Salt (BAY-205) is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth f...
T37820	Brain-Derived Basic Fibroblast Growth Factor (1-24) (bovine) (trifluoroacetate salt)
	Brain-derived basic fibroblast growth factor (1-24) (brain-derived bFGF) is a peptide fragment of brain-derived bFGF. bFGF is a peptide produced in bovine brain that is protective in a rat model of pressure-induced retin...
T74000	CP-547632 TFA		VEGFR
	CP-547632 TFA is an orally active, ATP-competitive inhibitor that potently targets VEGFR-2 and FGF kinases with IC50 values of 11 nM and 9 nM, respectively. It demonstrates selectivity for VEGFR-2 and bFGF over EGFR, PDG...		VEGFR
T69599	ABT-510
	ABT-510 is synthetic peptide that mimics the anti-angiogenic activity of the endogenous protein thrombospondin-1 (TSP-1). ABT-510 inhibits the actions of several pro-angiogenic growth factors important to tumor neovascul...
T67442	CGP-53716
	The growth factors, platelet-derived growth factor (PDGF) and basic fibroblast growth factor (bFGF) play major roles in enhanced smooth muscle cells growth in rodent blood vessels after vascular injury. Tyrosine kinase i...