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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7202 | ITE | AhR , Aryl Hydrocarbon Receptor | |
ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity. | |||
T1960 | YL-109 | AhR , Aryl Hydrocarbon Receptor | |
YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo. | |||
T21966 | MeBIO | GSK-3 , Aryl Hydrocarbon Receptor , CDK | |
MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β. | |||
TN1451 | Brevifolincarboxylic acid | AhR , Aryl Hydrocarbon Receptor , Glucosidase | |
Brevifolincarboxylic acid is a natural product isolated from Polygonum capitatum, it has inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincarboxylic acid is an α-glucosidase inhibitor with an IC50 of 3... | |||
T2448 | CH-223191 | CH 223191 | AhR , Aryl Hydrocarbon Receptor |
CH-223191 is a potent and specific antagonist for aryl hydrocarbon receptor (AhR). | |||
T5622 | BAY-218 | AHR antagonist 1 | AhR , Aryl Hydrocarbon Receptor |
BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of 39.9 nM in human cell line. | |||
T4608 | PDM2 | AhR , Aryl Hydrocarbon Receptor | |
PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist. | |||
T15410 | GNF351 | Aryl Hydrocarbon Receptor | |
GNF351 is a full antagonist of the aryl hydrocarbon receptor (AHR)with the capacity to inhibit both DRE-dependent and -independent activity. GNF351 is minimal toxicity in mouse or human keratinocytes. GNF351 competes wit... | |||
T4607 | CAY 10465 | CAY10465,CAY10465 Exclusive | AhR , Aryl Hydrocarbon Receptor |
CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM). | |||
T20625 | Prochloraz | Sporgon,Prelude | Estrogen Receptor/ERR , AhR , Androgen Receptor , Antifungal |
Prochloraz (Prelude) is a broad-spectrum contact imidazole fungicide. Prochloraz inhibits human placental microsomal aromatase in vitro (IC50 = 40 nM). Prochloraz also acts as an estrogen receptor (IC50s = 25 μM) and and... | |||
T10270 | BAY 2416964 | Aryl Hydrocarbon Receptor | |
BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist(example 192, IC50: 341 nM). It has the potential for cancer treatment. | |||
T10007 | 1,4-Chrysenequinone | Chrysene-1,4-dione | AhR |
1,4-Chrysenequinone (Chrysene-1,4-dione) is an activator of aryl hydrocarbon receptor (AhR). | |||
T3389 | Antitumor agent-21 | TRX818 | Others |
Antitumor agent-21 (TRX818) is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities. | |||
T6795 | Carbidopa | (S)-(-)-Carbidopa,Lodosyn | Decarboxylase , Aryl Hydrocarbon Receptor |
Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM). It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA. | |||
TQ0257 | FICZ | 6-Formylindolo[3,2-b]carbazole | Aryl Hydrocarbon Receptor |
FICZ (6-Formylindolo[3,2-b]carbazole) is a potent aryl agonist for the hydrocarbon receptor (AhR, Kd: 70 pM). | |||
T5786 | TETRAHYDROPIPERINE | Cosmoperine | P450 , TRP/TRPV Channel |
Tetrahydropiperine (Cosmoperine) is a natural product derived from piperine, can be used to treat convulsion, epilepsy, relieve pain, and control insects. | |||
T1831 | StemRegenin 1 | SR1 | AhR , Aryl Hydrocarbon Receptor |
StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor. | |||
T4928 | L-Kynurenine | (S)-Kynurenine | AhR , Aryl Hydrocarbon Receptor , Endogenous Metabolite |
L-Kynurenine ((S)-Kynurenine) is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has ... | |||
T0878 | Diosmin | Venosmine,Diosmil,Barosmin | Aryl Hydrocarbon Receptor , Norepinephrine |
Diosmin (Venosmine) is a bioflavonoid that strengthens vascular walls. | |||
T13276 | VAF347 | Aryl Hydrocarbon Receptor | |
VAF347 is a cell-permeable and highly affinity agonist of the aryl hydrocarbon receptor (AhR) with anti-inflammatory effects. |