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Carbidopa

Catalog No. T6795 CAS 28860-95-9

Synonyms: (S)-(-)-Carbidopa, Lodosyn, Lodosyn, (S)-(-)-Carbidopa

Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM). It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA.

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Carbidopa, CAS 28860-95-9

Pack Size	Availability	Price/USD
25 mg	In stock	81.00
100 mg	In stock	188.00
1 mL * 10 mM (in DMSO)	In stock	50.00

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Purity 98.00%

HNMR COA

Purity 98.01%

HNMR LCMS COA

Datasheet SDS

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM). It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA.
Targets&IC50	aromatic-L-amino-acid decarboxylase

Synonyms	(S)-(-)-Carbidopa , Lodosyn , Lodosyn , (S)-(-)-Carbidopa
Purity	98.00%
Molecular Weight	226.23
Formula	C10H14N2O4
CAS No.	28860-95-9

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 6 months

Solubility Information

DMSO: 4.5 mg/mL (20 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Durso, R., et al., Variable absorption of carbidopa affects both peripheral and central levodopa metabolism. J Clin Pharmacol, 2000. 40(8): p. 854-60. 2. Orlefors, H., et al., Carbidopa pretreatment improves image interpretation and visualisation of carcinoid tumours with 11C-5-hydroxytryptophan positron emission tomography. Eur J Nucl Med Mol Imaging, 2006. 33(1): p. 60-5.

Related compound libraries

This product is contained In the following compound libraries：

Natural Product Library for HTS Immunology/Inflammation Compound Library Selected Plant-Sourced Compound Library Polyphenolic Natural Product Library CNS-Penetrant Compound Library Drug Repurposing Compound Library Anti-Neurodegenerative Disease Compound Library Anti-Parkinson's Disease Compound Library

Related Products

Related compounds with same targets

4-Bromo-3-hydroxybenzoic acid Carbidopa Eflornithine hydrochloride hydrate Carbidopa monohydrate Tritoqualine L-Ornithine

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.