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BAY-218

Catalog No. T5622 CAS 2162982-11-6

Synonyms: AHR antagonist 1

AHR antagonist 1 is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of 39.9 nM in human cell line.

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BAY-218, CAS 2162982-11-6

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	AHR antagonist 1 is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of 39.9 nM in human cell line.
Targets&IC50	AHR in human cell line:39.9 nM (IC50)

Synonyms	AHR antagonist 1
Molecular Weight	401.82
Formula	C20H17ClFN3O3
CAS No.	2162982-11-6

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 250 mg/mL (622.17 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Ilona Gutcher, Christina Kober, Lars Roese,et al.Abstract 1288: Blocking tumor-associated immune suppression with BAY-218, a novel, selective aryl hydrocarbon receptor (AhR) inhibitor[J].10.1158/1538-7445.AM2019-1288 Published July 2019.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library Inhibitor Library Immunology/Inflammation Compound Library Nonsteroidal Anti-Inflammatory Compound Library Bioactive Compound Library

Related Products

Related compounds with same targets

Brevifolincarboxylic acid ITE BAY-218 PDM11 L-Kynurenine Tapinarof PDM2 CAY 10465

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Keywords

BAY-218 2162982-11-6 代谢免疫与炎症 AhR Aryl Hydrocarbon Receptor cancer human monocytic U937 cells AHR antagonist1 inhibit Inhibitor BAY218 aryl hydrocarbon receptor (AHR) U87 glioblastoma cells AHR antagonist 1 AHR antagonist-1 immune BAY 218 inhibitor

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