anti-hiv — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN2283	Tripterifordin		HIV Protease
	Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml.		HIV Protease
T12651	Rabdosiin	(+)-Rabdosiin	Others
	Rabdosiin ((+)-Rabdosiin) is a natural product, and has anti-allergic activity, anti-HIV activity and inhibition on DNA topoisomerase.		Others
T28578	Ro24-7429	Ro 24-7429,Ro-24-7429,Ro 247429	HIV Protease
	Ro24-7429 is an effective and orally active antagonist of HIV-1 transactivator protein Tat and an inhibitor of a runt-related transcription factor 1. Ro24-7429 has anti-HIV, antifibrotic, and anti-inflammatory effects.		HIV Protease
T3199	PTACH	NCH-51,Cpd 51	HIV Protease , HDAC
	PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM).		HIV Protease , HDAC
T11538	Hck-IN-1		HIV Protease , Src , Hck
	Hck-IN-1 is a selective Nef-dependent Hck inhibitor (IC50s: 2.8 μM and >20 μM for Nef:Hck complex and Hck) with antiretroviral activity. Hck-IN-1 is a direct and wide HIV-1 Nef antagonist with an IC50 of 100-300 nM for w...		HIV Protease , Src , Hck
T2S0731	Trilobatin	P-Phlorizin	Amylase
	Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentially inhibits the lipopolysaccharide (LPS)-induced inflammatory respon...		Amylase
T0492	Dimethyl fumarate	DMF	Reactive Oxygen Species , HIV Protease , Nrf2 , Endogenous Metabolite , Autophagy
	Dimethyl fumarate (DMF), a fumarate derivative, is used as antiinflammatory and immunomodulatory agent.
T0070	Pentoxifylline	Oxpentifylline,PTX,BL-191	HIV Protease , PDE , Adenosine Receptor , Autophagy
	Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet ...		HIV Protease , PDE , Adenosine Receptor , Autophagy
T11465	Lenacapavir	GS-6207	Others , HIV Protease
	Lenacapavir (GS-6207) is a potent capsid-targeting inhibitor of HIV replication. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells.		Others , HIV Protease
T20489	Benzalphthalide	NSC2824,NSC-2824,NSC 2824	HIV Protease
	Benzalphthalide (NSC-2824) is a chemical compound with anti-HIV activity.		HIV Protease
T68156	(Rac)-Telinavir		HIV Protease
	(Rac)-Telinavir shows anti-HIV activity.		HIV Protease
TQ0297	Cenicriviroc	TAK-652,TBR-652	HIV Protease , CCR
	Cenicriviroc (TAK-652) is an orally active, dual antagonist of CCR2/CCR5. It also inhibits both HIV-1 and HIV-2, and displays potent anti-infective and anti-inflammatory activity.		HIV Protease , CCR
T71665	INCB-9471		HIV Protease , CCR
	INCB-9471 is a CCR5 antagonist with anti-HIV activity and inhibits the interaction between HIV-1 gp120.		HIV Protease , CCR
T6256	YYA-021	YYA 021	gp120/CD4 , HIV Protease
	YYA-021 inhibits HIV entry, with high anti-HIV activity and low cytotoxicity.		gp120/CD4 , HIV Protease
T2239L	Raltegravir	MK-0518	HIV Protease , Integrase
	Raltegravir (MK-0518) is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV INFECTION.		HIV Protease , Integrase
T15210	Elsulfavirine	Elpida,VM-1500	HIV Protease
	Elsulfavirine (VM-1500) is an HIV-1 infection reverse transcriptase inhibitor. It is a new anti-HIV drug.		HIV Protease
T77059	Leronlimab	PRO 140	CCR
	Leronlimab (PRO 140) is a humanized IgG4 anti-CCR5 monoclonal antibody. leronlimumab has both anti-HIV and anti-tumor activity, inhibiting CCR-mediated HIV-1 virus and cancer cell metastasis in mouse tumor models. Leronl...		CCR
T22565	AMD-070 hydrochloride		CXCR
	AMD-070 hydrochloride is a CXCR4 antagonist, is useful for Anti HIV.		CXCR
T10111	3-Deazaadenosine hydrochloride		Others , HIV Protease
	3-Deazaadenosine hydrochloride is an inhibitor of S-adenosylhomocysteine hydrolase (Ki: 3.9 µM). It has anti-inflammatory, anti-proliferative, and anti-HIV activity.		Others , HIV Protease
T7624	DAPTA	DAPTA(TFA),D-Ala-peptide T-amide,Adaptavir	HIV Protease , CCR
	DAPTA (Adaptavir) is an inhibitor of CCR5, shows potent anti-HIV activities.		HIV Protease , CCR