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Search Results for " zag "

Targets

27

Compounds

2

Natural Products

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
TNU0541 8-Azaguanosine Nucleoside Antimetabolite/Analog
8-Azaguanosine is a purine nucleoside analog with a broad spectrum of antitumor activity and is used in the study of a variety of tumor diseases.
T25742 Linzagolix choline GNRH Receptor
Linzagolix choline is an orally available non-peptide gonadotropin-releasing hormone (GnRH) antagonist. It can be used to study pain associated with uterine fibroids and endometriosis.
T6236 Ozagrel OKY-046,Domenan Thrombin , Prostaglandin Receptor
Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral isch...
T16083 Mizagliflozin GSK-1614235 free base,KGA-3235 free base,DSP-3235 free base SGLT
Mizagliflozin (GSK-1614235 free base) is a sodium-glucose transporter inhibitor( Ki of 27 nM for human SGLT1). Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic drug that ca...
T12883 Fezagepras PBI-4050,Setogepram GPR
Fezagepras (Setogepram) is an orally active GPR40 agonist and is an antagonist or inverse agonist of GPR84 with anti-inflammatory, anti-fibrotic, and anti-proliferative actions.
T27837 Linzagolix GNRH Receptor
Linzagolix is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which is under development by Kissei Pharmaceutical and ObsEva for the treatment of uterine fibroids,...
T76726 Zagotenemab LY33003560 Microtubule Associated
Zagotenemab is a humanized antibody against the microtubule-associated protein tau that selectively regulates tau deposits in the brain. Zagotenemab can be used to study neurological disorders such as Alzheimer's disease...
T15159 Dorzagliatin HMS5552 Glucokinase
Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.
T6625 Ozagrel hydrochloride Ozagrel HCl,OKY-046 HCl Thrombin , Prostaglandin Receptor
Ozagrel hydrochloride (OKY-046 HCl) is a selective thromboxane A(2) synthetase inhibitor used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.
T12375 Fezagepras sodium Setogepram sodium salt,PBI-4050 sodium salt GPR
Fezagepras sodium (Setogepram sodium salt) is an orally active GPR40 agonist and is an antagonist or inverse agonist for GPR84, with anti-fibrotic, anti-inflammatory and anti-proliferative actions.
T76620 (D-Tyr5,D-Ser(tBu)6,Azagly10)-LHRH
(D-Tyr5,D-Ser(tBu)6,Azagly10)-LHRH, an analogue of luteinizing hormone-releasing hormone (LHRH), plays a pivotal role in reproductive control by promoting the pituitary release of luteinizing hormone (LH) and follicle-st...
T76615 (D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH
(D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH, an analogue of the luteinizing hormone-releasing hormone (LHRH), fundamentally mediates reproductive processes by promoting the secretion of pituitary luteinizing hormone (LH) and foll...
TNU0180 7-Deazaguanosine
Nucleoside Derivatives - 7-Deaza-purine nucleosides; Drugs and Inhibitors; Antiviral agent, anti-HCV
T69792 Atuzaginstat
Atuzaginstat is a bacterial protease lysine gingipain inhibitor.
TNU0275 8-Aza-7-bromo-7-deazaguanosine
8-Aza-7-bromo-7-deazaguanosine is a Nucleoside Derivative - 7-Deaza-8-aza-purine nucleoside; Halo-nucleoside; Scaffold and Template.
T71340 Mizagliflozin sebacate
Mizagliflozin sebacate is a sodium-glucose transporter inhibitor. It is expected to improve postprandial hyperglycemia by suppressing glucose absorption from the intestine with a novel mechanism of action different from...
TNU0174 7-Cyano-7-deazaguanosine
Nucleoside Derivatives - 7-Deaza-purine nucleosides;Naturally modified ribo-nucleosides
TNU0173 7-(N-Acetylaminomethyl)-7-deazaguanosine
Nucleoside Derivatives –7-Deaza-purine nucleosides; Amino nucleosides
T76616 (D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH
(D-Ser4, D-Ser(tBu)6, Azagly10)-LHRH, an analogue of luteinizing hormone-releasing hormone (LHRH), plays a pivotal role in reproductive regulation by promoting the secretion of pituitary luteinizing hormone (LH) and foll...
T37388 Afizagabar
Afizagabar (S44819) is a first-in-class, competitive, and selective antagonist at the GABA-binding site of the α5-GABAAR, with an IC50 of 585 nM for α5β2γ2 and a Ki of 66 nM for α5β3γ2. Afizagabar enhances hippocampal sy...
T78379 9-Deazaguanine Others
9-Deazaguanine is a nucleoside analog that exhibits potent inhibitory activity against purine nucleoside phosphorylase (PNP) [1].
T19148 5-Aza-7-deazaguanine Others
5-Aza-7-deazaguanine is a substrate for E. coli purine nucleoside phosphorylase (wild-type/Ser90Ala mutant) in the synthesis of base-modified nucleosides.
T6236L Ozagrel Sodium KCT 0809,KCT-0809,Xanbo,KCT0809,Cataclot
Ozagrel Sodium is a thromboxane A2 synthase inhibitor. It is used to treat cerebrovascular diseases.
TNU1526 N2-iso-Butyryl-8-azaguanosine
N2-iso-Butyryl-8-azaguanosine is a Nucleoside Derivative - 8-Modified purine nucleoside.
T77084 Mezagitamab
Mezagitamab (TAK-079), an IgG1λ anti-CD38 monoclonal antibody, functions by depleting tumor cells that express CD38 through both antibody and complement-dependent cytotoxicity. It shows potential for use in the treatment...
T31406 Dezaguanine Dezaguanina,NSC 261726,CI-908,CI 908
Dezaguanine is a novel antipurine antimetabolite with significant activity against transplantable rodent solid tumors, particularly breast adenocarcinoma.
T39673 Zagociguat
Zagociguat is a soluble guanylate cyclase stimulator that enhances nitric oxide (NO) signaling, resulting in increased production of cyclic guanosine monophosphate. This compound shows promise for investigating non-centr...

Compounds

8-Azaguanosine
TNU0541
Synonym:
Target: Nucleoside Antimetabolite/Analog
Linzagolix choline
T25742
Synonym:
Target: GNRH Receptor
Ozagrel
T6236
Synonym: OKY-046,Domenan
Target: Thrombin, Prostaglandin Receptor
Mizagliflozin
T16083
Synonym: GSK-1614235 free base,KGA-3235 free base,DSP-3235 free base
Target: SGLT
Fezagepras
T12883
Synonym: PBI-4050,Setogepram
Target: GPR
Linzagolix
T27837
Synonym:
Target: GNRH Receptor
Zagotenemab
T76726
Synonym: LY33003560
Target: Microtubule Associated
Dorzagliatin
T15159
Synonym: HMS5552
Target: Glucokinase
Ozagrel hydrochloride
T6625
Synonym: Ozagrel HCl,OKY-046 HCl
Target: Thrombin, Prostaglandin Receptor
Fezagepras sodium
T12375
Synonym: Setogepram sodium salt,PBI-4050 sodium salt
Target: GPR
(D-Tyr5,D-Ser(tBu)6,Azagly10)-LHRH
T76620
Synonym:
Target:
(D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH
T76615
Synonym:
Target:
7-Deazaguanosine
TNU0180
Synonym:
Target:
Atuzaginstat
T69792
Synonym:
Target:
8-Aza-7-bromo-7-deazaguanosine
TNU0275
Synonym:
Target:
Mizagliflozin sebacate
T71340
Synonym:
Target:
7-Cyano-7-deazaguanosine
TNU0174
Synonym:
Target:
7-(N-Acetylaminomethyl)-7-deazaguanosine
TNU0173
Synonym:
Target:
(D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH
T76616
Synonym:
Target:
Afizagabar
T37388
Synonym:
Target:
9-Deazaguanine
T78379
Synonym:
Target: Others
5-Aza-7-deazaguanine
T19148
Synonym:
Target: Others
Ozagrel Sodium
T6236L
Synonym: KCT 0809,KCT-0809,Xanbo,KCT0809,Cataclot
Target:
N2-iso-Butyryl-8-azaguanosine
TNU1526
Synonym:
Target:
Mezagitamab
T77084
Synonym:
Target:
Dezaguanine
T31406
Synonym: Dezaguanina,NSC 261726,CI-908,CI 908
Target:
Zagociguat
T39673
Synonym:
Target:
Cat No. Product Name Synonyms Targets
TN7185 7-Cyano-7-deazaguanine 7-CN-7-deazaG Others
7-Cyano-7-deazaguanine (7-CN-7-deazaG) is a marine derived natural products found in Streptomyces qinglanensis.
T2218 8-Azaguanine Azaguanine-8,SK 1150,NSC-749,SF-337 Nucleoside Antimetabolite/Analog , Others , Endogenous Metabolite
8-Azaguanine (SK 1150) is a purine analogue with potential antineoplastic activity.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-03117 Zinc Alpha 2 Glycoprotein/AZGP1 Protein, Human, Recombinant (His) Human HEK293 Cells
Alpha-2-glycoprotein, also known as AZGP1, belongs to the MHC class I family. It can be detected in body fluids such as serum, sweat, and seminal and breast cyst fluids. It has been shown that alpha-2-glycoprotein can st...
TargetMol