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Ozagrel Sodium

Catalog No. T6236L CAS 189224-26-8

Synonyms: KCT 0809, KCT-0809, Xanbo, KCT0809, Cataclot

Ozagrel Sodium is a thromboxane A2 synthase inhibitor. It is used to treat cerebrovascular diseases.

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Ozagrel Sodium, CAS 189224-26-8

Pack Size	Availability	Price/USD
5 mg	5 days	$ 30.00
10 mg	5 days	$ 59.00
1 mL * 10 mM (in DMSO)	5 days	$ 52.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Ozagrel Sodium is a thromboxane A2 synthase inhibitor. It is used to treat cerebrovascular diseases.

Synonyms	KCT 0809, KCT-0809, Xanbo, KCT0809, Cataclot
Molecular Weight	251.24
Formula	C13H12N2NaO2
CAS No.	189224-26-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Soluble

References and Literature

1. Park SI, Park SK, Jang KS, Han YM, Kim CH, Oh SJ. Preischemic neuroprotective effect of minocycline and sodium ozagrel on transient cerebral ischemic rat model. Brain Res. 2015 Mar 2;1599:85-92. doi: 10.1016/j.brainres.2014.12.051. Epub 2014 Dec 31. PubMed PMID: 25555371. 2. Wada T, Yasunaga H, Horiguchi H, Fushimi K, Matsubara T, Nakajima S, Yahagi N. Ozagrel for Patients With Noncardioembolic Ischemic Stroke: A Propensity Score-Matched Analysis. J Stroke Cerebrovasc Dis. 2016 Aug 23. pii: S1052-3057(16)30261-0. doi: 10.1016/j.jstrokecerebrovasdis.2016.07.044. [Epub ahead of print] PubMed PMID: 27567296. 3. Tange M, Yoshida M, Hazekawa M, Haraguchi T, Nakai Y, Uchida T. Prediction of compatibility between ozagrel sodium preparation for injection and calcium on the basis of the solubility product. Chem Pharm Bull (Tokyo). 2013;61(5):567-71. Epub 2013 Mar 1. PubMed PMID: 23449252. 4. Zhang J, Yang J, Chang X, Zhang C, Zhou H, Liu M. Ozagrel for acute ischemic stroke: a meta-analysis of data from randomized controlled trials. Neurol Res. 2012 May;34(4):346-53. doi: 10.1179/1743132812Y.0000000022. PubMed PMID: 22643078.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Ozagrel Sodium 189224-26-8 KCT 0809 KCT-0809 Xanbo KCT0809 Cataclot inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.