timp — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1606	Fasudil	HA-1077,AT877	ROCK , Serine/threonin kinase , Calcium Channel , PKA , PKC , Autophagy
	Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
T3060	Fasudil hydrochloride	Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877	ROCK , Serine/threonin kinase , Calcium Channel , HIV Protease , PKA , PKC , Autophagy
	Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
T15647	Tipelukast	MN 001,KCA 757	Leukotriene Receptor
	Tipelukast (KCA 757) is a novel orally available leukotriene receptor antagonist with anti-inflammatory activity that reduces fibrosis and down-regulates TIMP-1, type 1 collagen.Tipelukast is used in the study of asthma.		Leukotriene Receptor

Compounds

Fasudil

T1606

Synonym: HA-1077,AT877

Target: ROCK, Serine/threonin kinase, Calcium Channel, PKA, PKC, Autophagy

Fasudil hydrochloride

T3060

Synonym: Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877

Target: ROCK, Serine/threonin kinase, Calcium Channel, HIV Protease, PKA, PKC, Autophagy

Tipelukast

T15647

Synonym: MN 001,KCA 757

Target: Leukotriene Receptor

Cat No.	Product Name	Synonyms	Targets
T2A2481	Taurochenodeoxycholic Acid	Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine	Apoptosis , TNF , Caspase , Endogenous Metabolite
	Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.		Apoptosis , TNF , Caspase , Endogenous Metabolite
TN2215	Taurochenodeoxycholic acid sodium	Sodium taurochenodeoxycholate	Apoptosis , Endogenous Metabolite
	Taurochenodeoxycholic acid sodium (Sodium taurochenodeoxycholate) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and...		Apoptosis , Endogenous Metabolite
T5S0053	Coptisine	Coptisin	Indoleamine 2,3-Dioxygenase (IDO)
	1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myocardial I/R likely through suppressing myocardial ...		Indoleamine 2,3-Dioxygenase (IDO)

Natural Products

Taurochenodeoxycholic Acid

T2A2481

Synonym: Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine

Target: Apoptosis, TNF, Caspase, Endogenous Metabolite

Taurochenodeoxycholic acid sodium

TN2215

Synonym: Sodium taurochenodeoxycholate

Target: Apoptosis, Endogenous Metabolite

Coptisine

T5S0053

Synonym: Coptisin

Target: Indoleamine 2,3-Dioxygenase (IDO)

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01107	TIMP-1 Protein, Human, Recombinant	Human	HEK293 Cells
	TIMP-1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 21 kDa and the accession number is P01033.
TMPY-01485	TIMP-1 Protein, Mouse, Recombinant	Mouse	HEK293 Cells
	TIMP-1 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 21 kDa and the accession number is P12032.
TMPY-00154	TIMP-1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	TIMP-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is P01033.
TMPY-00932	TIMP-1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	TIMP-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22 kDa and the accession number is P01033.
TMPY-02912	TIMP-1 Protein, Rat, Recombinant	Rat	HEK293 Cells
	TIMP-1 Protein, Rat, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 21.5 kDa and the accession number is P01860.
TMPK-00093	TIMP-1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Tissue inhibitor of metalloprotease-1 (TIMP-1) is a tissue inhibitor of matrix metalloproteinases (MMPs). It however exerts multiple effects on biological processes, such as cell growth, proliferation, differentiation an...
TMPY-01868	TIMP-2 Protein, Human, Recombinant	Human	HEK293 Cells
	TIMP-2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 22 kDa and the accession number is A0A140VK57.
TMPY-00933	TIMP-2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	TIMP-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is A0A140VK57.
TMPJ-00916	TIMP-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mouse Metalloproteinase inhibitor 2(TIMP-2), belongs to a family of proteins that regulate the activation and proteolytic activity of matrix metalloproteinases (MMPs). There are four mammalian members of the family; TIMP...
TMPJ-01289	TIMP-4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene, belongs to the protease inhibitor I35 (TIMP) family. The protein complexes with metalloproteinases (such as collagenases) and irreve...
TMPJ-00101	TIMP-2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Tissue inhibitors of metalloproteinases or TIMPs are a family of proteins that regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases (MMPs). There are four members of the...
TMPH-02782	TIMP4 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	TIMP4 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-01665	TIMP3 Protein, Human, Recombinant (His)	Human	E. coli
	Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to ac...
TMPK-01286	MMP-8 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Alteration of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) expression has been studied for various cardiac diseases, including dilated cardiomyopathy (DCM), with the significance o...
TMPJ-00157	CD82 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemoki...