sam — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T30798	Cerlapirdine	PF05212365,P -05212365,SAM-531,SAM531,PF-05212365,SAM 531,WAY-262,531	5-HT Receptor
	Cerlapirdine (PF-05212365) is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine is already in clinical development for the treatment of cognitive disorders related to Alzhei...		5-HT Receptor
T12833	Sardomozide	CGP 48664,SAM-486A	Others
	Sardomozide is an inhibitor of S-adenosylmethionine decarboxylase (SAMDC)(IC50 of 5 nM).		Others
T9050	AG-270		Others , Methionine Adenosyltransferase (MAT)
	AG-270 is an allosteric and orally active inhibitor of MAT2A.		Others , Methionine Adenosyltransferase (MAT)
T11285	FIDAS-5		Others
	FIDAS-5, a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM, competitively inhibits S-adenosylmethionine (SAM) binding to MAT2A. It exhibits anticancer activities.		Others
T11284	FIDAS-3		Others , Wnt/beta-catenin , Methionine Adenosyltransferase (MAT)
	FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities by effectively competing with S-adenosylmethionine (SAM) for ...
T70962	MHY219
	MHY219 is a novel HDAC inhibitor. MHY219 induces apoptosis via up-regulation of androgen receptor expression in human prostate cancer cells. MHY219 was shown to enhance the cytotoxicity on DU145 cells (IC50, 0.36 μM) whe...
T68330	Cerlapirdine hydrochloride
	Cerlapirdine, also known as SAM-531, WAY-262,531 and PF-05212365, is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine has been in clinical development for the treatment of...
T8227	5'-Methylthioadenosine	Methylthioadenosine,5'-(Methylthio)-5'-deoxyadenosine,5'-Deoxy-5'-(methylthio)adenosine,5'-S-Methyl-5'-thioadenosine	Endogenous Metabolite
	5'-Methylthioadenosine (Methylthioadenosine) is produced from S-adenosylmethionine and behaves as a powful inhibitory product.		Endogenous Metabolite
TN6783	Corysamine chloride	CORYSAMINE CHLORIDE(RG)	AChE
	Corysamine chloride (CORYSAMINE CHLORIDE(RG)) was identified to inhibit the activity of ACHE.		AChE
T67888L	Samidorphan HCl	Samidorphan HCl（852626-89-2 free base）	Opioid Receptor
	Samidorphan HCl is an orally active and highly potent modulator of the opioid system that binds to μ‐opioid, κ‐opioid, and delta-opioid receptors. Samidorphan HCl is a novel μ-opioid receptor antagonist, a partial agonis...		Opioid Receptor
T9567	Samatasvir	ATOLIHZIXHZSBA-BTSKBWHGSA-N,IDX719	HCV Protease
	Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A.		HCV Protease
T77748	Tusamitamab		Others
	Tusamitamab is an IgG1 monoclonal antibody targeting CEACAM5 and is the naked antibody to Tusamitamab ravtansine.Tusamitamab can be used to synthesize the antibody-activator coupling Tusamitamab ravtansine.		Others
T3S1873	Talatisamine		Potassium Channel
	1. Talatisamine (12 μM) and TEA (5mM) inhibits the enhanced I(K) caused by Aβ4 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss related apoptotic response. 2. Talat...		Potassium Channel
T8238	Fosamprenavir Calcium Salt	Diallyl Trisulfide,GW433908G	HIV Protease
	Fosamprenavir Calcium Salt (GW433908G) (GW433908G) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility. Fosamprenavir Calcium Salt has Anti-HIV infection.		HIV Protease
T7387	Ceftaroline fosamil	TAK-599,PPI0903	Antibacterial , Antibiotic
	Ceftaroline fosamil (TAK-599) is a cephalosporin, with activity against Gram-positive pathogens.		Antibacterial , Antibiotic
T4708	D-N-Acetylgalactosamine	D-GalNAc,N-Acetyl-D-galactosamine	Others , Endogenous Metabolite
	D-N-Acetylgalactosamine (N-Acetyl-D-galactosamine) is an important constituent of brain heteropolysaccharides (glycoproteins).		Others , Endogenous Metabolite
T68136	(Iso)-Samixogrel		COX , Carbonic Anhydrase
	(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.		COX , Carbonic Anhydrase
T19655	N-Acetyl-D-mannosamine	DEXM74,ManNAc,DEX M 74,DEX M-74,N-Acetylmannosamine hydrate,DEX-M-74,N-Acetylmannosamine	Antibacterial
	N-Acetyl-D-mannosamine (ManNAc) is a drug potentially for the treatment of hereditary inclusion body myopathy.		Antibacterial
T4725	N-Acetyl-D-mannosamine	2-ACETAMIDO-2-DEOXY-D-MANNOPYRANOSE HYDRATE	Others , Endogenous Metabolite
	N-Acetyl-D-mannosamine (2-ACETAMIDO-2-DEOXY-D-MANNOPYRANOSE HYDRATE) is a monosaccharide that is used as a precursor in the chemical or enzymatic synthesis of the neuraminic acids found in glycolipids and glycoproteins. ...		Others , Endogenous Metabolite
T3413	5-O-Methylvisammioside	5-O-Methylvisamminol glucoside,4'-O-β-D-Glucosyl-5-O-methylvisamminol	Others
	5-O-Methylvisammioside (4'-O-β-D-Glucosyl-5-O-methylvisamminol) is a natural product isolated from Saposhnikovia Divaricata.		Others