Search Result

Search Results for " pdi "

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T24608	PDI-IN-P1	PDI inhibitor P1,PDIINP1,PDI-inhibitor-P1
	PDI-IN-P1 is an inhibitor of protein disulfide isomerase.
T25821	ML359	ML-359,ML 359	Others
	ML359 is a protein disulfide isomerase inhibitor.		Others
T6800	CCF642	AC1LYELL	Others
	CCF642 (AC1LYELL) is a novel PDI-inhibiting compound with antimyeloma activity.		Others
T8640	G6PDi-1		Dehydrogenase
	G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production.		Dehydrogenase
T30473	Bis-hema ipdi
	Bis-hema ipdi is a bioactive chemical.
T5453	3-Methyltoxoflavin	3-methyl toxoflavin	Others
	3-Methyltoxoflavin (3-methyl toxoflavin) is an effective inhibitor of protein disulfide isomerase (PDI) and its IC50 value is 170 nM.		Others
T5534	LOC14		Others
	LOC14 to be the most potent PDI inhibitor reported to date( EC50 : 500 nM)		Others
T41277	PACMA 31		Others
	PACMA 31 is an irreversible and covalent inhibitor of protein disulfide isomerase (PDI) with an IC50 of 10 μM. PACMA 31 significantly suppresses ovarian tumor growth and exhibits tumor targeting ability.		Others
T11141	E64FC26		Others
	E64FC26 is a potent protein disulfide isomerase (PDI) family pan-inhibitor with antitumor activity, inhibits PDIA1, PDIA3, PDIA4, TXNDC5 and PDIA6, and can be used in the study of multiple myeloma and pancreatic cancer.		Others
T71589	AS15
	AS15 is a novel covalent nanomolar inhibitor of protein disulfide isomerase (PDI).
T69700	BAP2
	BAP2 is a novel inhibitor of protein disulfide isomerase (PDI).
T19505	PBDB-T		Others
	PBDB-T serves as a wide-bandgap polymer donor within polymer solar cells that utilize Perylene Diimide (PDI) as the base.		Others
T69718	Bacitracin F
	Bacitracin F is a major Bacitracin analog -- a peptide antibiotic used as an inhibitor of protein disulfide isomerase (PDI).
T35608	16F16
	16F16 is a protein disulfide isomerase (PDI) inhibitor.1It inhibits PDI reductase activity in an enzyme assay when used at concentrations ranging from 1 to 100 μg/ml.116F16 reduces PC12 cell apoptosis induced by the misf...
T39812	(E/Z)-E64FC26	(E/Z)-E64FC26
	(E/Z)-E64FC26 is a mixture complex comprising E-E64FC26 and Z-E64FC26. E-E64FC26 is a highly potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC50 values of 1.9, 20.9, 25.9, 16.3, and 25.4 μM ag...

Compounds

PDI-IN-P1

T24608

Synonym: PDI inhibitor P1,PDIINP1,PDI-inhibitor-P1

Target:

ML359

T25821

Synonym: ML-359,ML 359

Target: Dehydrogenase

Synonym: 3-methyl toxoflavin

Synonym: (E/Z)-E64FC26

Target:

Cat No.	Product Name	Synonyms	Targets
T4S1057	Tripdiolide		IL Receptor , TNF
	Tripdiolide has cytotoxic, and anti-rheumatic activities, it suppresses pro-inflammatory gene expression, may be effective therapy for lupus nephritis.		IL Receptor , TNF
T3752	4-Hydroxybenzyl alcohol	4-Methylolphenol,P-Methylolphenol	Apoptosis , Endogenous Metabolite
	4-Hydroxybenzyl alcohol (P-Methylolphenol) exhibits beneficial effects in cerebral ischemic injury, has neuroprotective effect through upregulation of Nrf2, Prdx6, and PDI expression via the PI3K/Akt pathway. 4-Hydroxybe...		Apoptosis , Endogenous Metabolite
T74207	Ribostamycin
	Ribostamycin (Vistamycin), a broad-spectrum aminoglycoside antibiotic, demonstrates efficacy against both Gram-Negative and Gram-Positive bacterial infections. Additionally, it inhibits the chaperone activity of PDI [1] ...
T82003	Juniferdin
	Juniferdin, a Protein disulfide isomerase (PDI) inhibitor with an IC50 of 3.5 μM, is designed to prevent HIV transmission. It exhibits cytotoxic properties and inhibits platelet aggregation [1].

Natural Products

Tripdiolide

T4S1057

Synonym:

Target: IL Receptor, TNF

4-Hydroxybenzyl alcohol

T3752

Synonym: 4-Methylolphenol,P-Methylolphenol

Target: Apoptosis, Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01012	P4HB Protein, Human, Recombinant (His)	Human	HEK293 Cells
	P4HB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.4 kDa and the accession number is A0A024R8S5.
TMPY-00021	PADI4 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Protein-arginine deiminase type-4, also known as HL-6 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type I V and PADI4, is a cytoplasm and nucleus protein that belongs to the protein arginine deiminase f...
TMPH-03318	IL-11 Protein, Rat, Recombinant (His & PDI)	Rat	P. pastoris (Yeast)
	IL-11 Protein, Rat, Recombinant (His & PDI) is expressed in yeast with N-6xHis-PDI tag. The predicted molecular weight is 78.0 kDa and the accession number is Q99MF5.
TMPY-01795	P4HB Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	P4HB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.2 kDa and the accession number is P09103.
TMPK-00501	PADI4 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	E. coli
	Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide anti...
TMPK-00502	PADI4 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated	Cynomolgus	E. coli
	Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide anti...
TMPK-01238	PADI4 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated	Human	E. coli
	Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide anti...
TMPJ-00532	PADI4 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyz...
TMPJ-01124	PDIA6 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Protein Disulfide-Isomerase A6 (PDIA6) is a 48.5kDa protein that belongs to the protein disulfide isomerase family (PDI). PDIA6 is an enzyme in the endoplasmic reticulum in eukaryotes which catalyzes the formation and br...
TMPJ-00935	PDIA3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	PDIA3 protein is also known as Protein disulfide-isomerase A3. It is a protein that in humans is encoded by the PDIA3 gene.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones...
TMPJ-01225	PDILT Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Protein Disulfide-Isomerase-Like Protein of the Testis (PDILT) is a protein that belongs to the protein disulfide isomerase family. Human PDILT is synthesized as a 584 amino acid precursor that contains an 20 amino acid ...
TMPJ-00461	PDIA5 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Protein disulfide-isomerase A5 is a 519 amino acids protein that belongs to the protein disulfide isomerase family.It contains 3 thioredoxin domains.It can catalyze the rearrangement of -S-S- bonds in proteins.
TMPH-02851	PDIA2 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded protei...
TMPJ-01274	ERO1L Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ERO1-Like Protein α (ERO1L) is an enzyme that belongs to the EROs family. ERO1L is expressed at high level in esophagus and upper digestive tract. ERO1L is an essential oxidoreductase that oxidizes proteins in the endopl...
TMPY-02890	ERP27 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	ERP27 contains 1 thioredoxin domain and is a noncatalytic member of the protein disulfide isomerase family. Protein disulfide isomerases (PDIs) constitute a family of structurally related enzymes which catalyze disulfide...
TMPY-04205	AGR3 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	Anterior gradient protein (AGR) 3 is a highly related homologue of pro-oncogenic AGR2 and belongs to the family of protein disulfide isomerases. AGR3 was found in breast, ovary, prostate, and liver cancer, it is associat...
TMPJ-00056	AG-2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcin...