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Search Results for " orally "

20

Compounds

Cat No. Product Name Synonyms Targets
T8348 Phentolamine Adrenergic Receptor
Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist
T35862 Cucurbit[8]uril Others
Cucurbit[8]uril is a highly effective and safe supramolecular compound that promotes protein heterodimerization. It selectively induces the heterodimerization of methylviologen and naphthalene functionalized proteins, de...
T8345 Carbutamide Others
Carbutamide is a sulfonylurea antidiabetic agent with hypoglycemic activity.
T8580 Bupranolol Adrenergic Receptor
Bupranolol is an antagonist of β2-adrenergic receptor and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic.
T9565 OSBPL7-IN-1 Others
OSBPL7-IN-1 is an orally active inhibitor of oxysterol binding protein like 7 (OSBPL7). OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression[1].
T9692 Paltusotine Somatostatin
Paltusotine is a nonpeptide, small molecule somatostatin type 2 (SST2) receptor agonist with high oral bioavailability. Paltusotine maintains GH and IGF-1 levels in acromegaly patients
T9732 VY-3-135 Fatty Acid Synthase
VY-3-135 is a metastasis inhibitor and an acetyl-CoA synthetase 2 (ACSS2) modulator.
T1292 Tiapride hydrochloride Dopamine Receptor
Tiapride is a selective blocker of D2/3 dopamine receptors in the brain. It is used in the therapy of various psychiatric and neurological disorders containing dyskinesia, negative symptoms of psychosis, alcohol withdraw...
T8734 Choline Others
Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins
T34896 Tofisopam Emandaxin,Grandaxin Others
Tofisopam (Grandaxin) is a 2,3-benzodiazepine compound with anxiolytic activity that can be taken orally.
T15500 HPi1 Others , Antibacterial
HPi1 is a selective and orally active antimicrobial against Helicobacter pylori (IC50: 0.24 μM and a MIC of 0.08-0.16 μg/mL). HPi1 is inactive against other Xaliproden, including the gut commensals, Lactobacillus reuteri...
T9346 CVN424 GPR
CVN424 is a selective and novel GPR6 Inverse agonist effective in models of Parkinson Disease.
T16115 MLi-2 LRRK2
MLi-2 is a structurally novel, highly potent, and selective LRRK2 kinase inhibitor with central nervous system activity. MLi-2 exhibits exceptional potency in a purified LRRK2 kinase assay in vitro (IC50 = 0.76 nM), a ce...
T3306 PF-04418948 PF 04418948,PF04418948 Prostaglandin Receptor
PF-04418948 is a potent EP2 receptor antagonist (IC50 = 16 nM for human EP2 receptors). Displays over 2000-fold selectivity for EP2 receptors over EP1, EP3, EP4, DP1 amd CRTH2 receptors; exhibits <30% binding at a divers...
TN2081 Maohuoside A MAPK
Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways.
T9214 ELOVL6-IN-1 Others
ELOVL6-IN-1 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse ELOVL6 activities, with an IC50 value of 0.350 μM. ELOVL6-IN-1 inhibits ELOVL6 in a noncompetitive manner...
T9683 VX-150 Sodium Channel
VX-150 is a highly selective NaV1.8 inhibitor relative to the other sodium channel subtypes (>400-fold).
T9215 ELOVL6-IN-2 Others
ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.
T2013 Ponalrestat Reductase
Ponalrestat is an aldose reductase inhibitor.
T39695 ARD-2128 Androgen Receptor
ARD-2128 is a highly potent, orally bioavailable PROTAC (proteolysis-targeting chimera) degrader of the androgen receptor (AR), effectively diminishing AR protein levels, suppressing AR-regulated gene expression in tumor...
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