ns3 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T39503	Hepatitis Virus C NS3 Protease Inhibitor 2
	Hepatitis Virus C NS3 Protease Inhibitor 2 is a peptide inhibitor derived from a product that targets the NS3 protease of the hepatitis C virus (HCV). Its inhibitory activity against the NS3 protease is characterized by ...
T62932	NS2B/NS3-IN-2
	NS2B/NS3-IN-2 is a potent, covalent inhibitor of dengue virus (DENV) NS2B/NS3 (IC50: 6.0 nM, Ki: 0.66 μM). NS2B/NS3-IN-2 significantly increases cell viability and is not cytotoxic.
T60458	NS2B/NS3-IN-4
	Compound 34e (NS2B/NS3-IN-4) is an allosteric inhibitor of the DENV2 and ZIKV NS2B/NS3 proteases, exhibiting IC50 values of 0.69 µM for DENV2 and 1.04 µM for ZIKV NS2B/NS3 proteases [1].
T62104	NS2B/NS3-IN-5
	NS2B/NS3-IN-5 (Compound 25b) is a variant of the DENV2 and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 0.67 μM and 4.38 μM for the NS2B/NS3 protease of ZIKV and DENV2, respectively.
T60881	NS2B/NS3-IN-3
	NS2B/NS3-IN-3 (Compd 66) is an inhibitor of Flavivirus NS2B-NS3 protease [1] .
T62437	NS2B/NS3-IN-6
	NS2B/NS3-IN-6 (Compound 1a) is a variant of the DENV and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 2.23 μM and 25.2 μM for the NS2B/NS3 protease of ZIKV and DENV, respectively.
T72887	NS2B/NS3-IN-7
	NS2B/NS3-IN-7 is a highly potent inhibitor of the Zika virus NS2B-NS3 protease, possessing a Ki value of 2.33 nM. It effectively reduces the number of ZIKV-infected cells.
T78653	NS2B/NS3-IN-3 hydrochloride		Virus Protease
	NS2B/NS3-IN-3 hydrochloride is a Flavivirus NS2B-NS3 protease inhibitor [1].		Virus Protease
T2718	Palmatine chloride		Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
	Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.		Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
T22394	Paritaprevir	ABT450,ABT-450,Veruprevir	HCV Protease
	Paritaprevir (ABT450) is an inhibitor of non-structural protein 3/4A protease with EC50 values of 1 and 0.21 nM for HCV 1a and HCV 1b, respectively.		HCV Protease
T5S0802	Palmatine	Berbericinine,Burasaine	Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase
	1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,...
T5429	Theaflavin 3,3'-digallate	8-Gingerol,TFDG	Virus Protease , Antioxidant , HIV Protease , HSV
	Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul...		Virus Protease , Antioxidant , HIV Protease , HSV
T33480	Montirelin	NS 3,Montirelinum,CNK 602A,CNK-603
	Montirelin is an analog of thyrotropin-releasing hormone.
T16347	NS3623		Potassium Channel
	NS3623 is an activator of human ether-a-go-go-related gene potassium channels. NS3623 has a dual mode of action, being an inhibitor of hERG1 channels. NS3623 activates the IKr and Ito currents and has an antiarrhythmic e...		Potassium Channel
T9542	NS3861		AChR
	NS3861 is an agonist of nicotinic acetylcholine receptors (nAChRs) and bind with high affinity to heteromeric α3β4 and α4β2 nAChRs. NS3861 displays the β-subunit preference and a complete lack of activation at α4-contain...		AChR
T22119	NS3694		Apoptosis
	NS3694 is an inhibitor of apoptosis and inhibits apoptosome formation and caspase activation.		Apoptosis
T15582	InS3-54A18		STAT
	inS3-54A18 is an effective inhibitor of STAT3. inS3-54A18 has anticancer effects.		STAT
T27613	InS3-54-A26		STAT
	inS3-54-A26 is an inhibitor of the DNA-binding domain of STAT3. inS3-54-A26 suppresses tumor growth, metastasis and the gene expression of STAT3.		STAT
T4612	NS309		EGFR , Potassium Channel , HER
	NS309 is a nonselective activator of small- and intermediate-conductance Ca2+-activated K+ (SK/KCa2 and IK/KCa3.1) channels (EC50s range from 0.12-1.2 µM for SK channels and 10-90 nM for IK channels). It can also activat...		EGFR , Potassium Channel , HER
T81642	NS2B-NS3pro-IN-1		Virus Protease
	NS2B-NS3pro-IN-1, a potent Zika Virus NS2B-NS3 protease inhibitor, exhibits an EC50 of 50 μM and is significant in the ZIKV replication cycle [1].		Virus Protease