nox — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T83972	NOX-6-18	GPR132 antagonist 1,GPR132-B-160	GPR
	NOX-6-18 (GPR132-B-160) is a highly potent and selective GPR132 antagonist with insulinotropic activity that modulates macrophage reprogramming in pancreatic islets and reduces weight gain.		GPR
T33716	Norathiol	NOX 100,NOX100,NOX-100
	Norathiol(NOX-100) is nitric oxide (NO) scavenging agent that may be used to prevent hypotension during hemodialysis and septic shock.
T4359	VAS2870		NADPH
	VAS2870 is an inhibitor of NADPH oxidase (NOX).		NADPH
T8107	GLX351322		NADPH-oxidase , NADPH
	GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.		NADPH-oxidase , NADPH
T15433	GSK2795039		Apoptosis , Reactive Oxygen Species , ROS , NADPH
	GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2 (NOX2) (pIC50: 6 in different cell-free assays).		Apoptosis , Reactive Oxygen Species , ROS , NADPH
T22990	ML-090	Fluoflavine	NADPH-oxidase , Others
	ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).		NADPH-oxidase , Others
T68796	Thr101
	Thr101, also known as NOX Inhibitor VII, is a dose-dependent inhibitor of HDAC1, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, and HDAC9. Thr101 is also a NOX inhibitor.
T6099	Setanaxib	GKT137831	NADPH-oxidase , Ferroptosis , NADPH
	Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.		NADPH-oxidase , Ferroptosis , NADPH
T7191	Diphenyleneiodonium chloride	DPI	NOS , Reactive Oxygen Species , NADPH , TRP/TRPV Channel
	Diphenyleneiodonium chloride (DPI)(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 μM, respectively),and displays broad-spectrum bactericidal activity.		NOS , Reactive Oxygen Species , NADPH , TRP/TRPV Channel
T8408	GKT136901	AK120765	NADPH-oxidase , NADPH
	GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite		NADPH-oxidase , NADPH
T10353	APX-115 free base	Ewha-18278 free base	NADPH-oxidase , NADPH
	APX-115 free base (Ewha-18278 free base) (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents kid...		NADPH-oxidase , NADPH
T3263	(6R,7S)-Cefminox sodium heptahydrate	Meicelin,Cefminox Sodium,Alteporina,Tencef	Antibiotic
	(6R,7S)-Cefminox sodium heptahydrate (Meicelin) is a broad-spectrum, bactericidal cephalosporin antibiotic. It is especially effective against Gram-negative and anaerobic bacteria.		Antibiotic
T66390	4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide
	4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide is an aromatic enigma that is is a metabolite of the antitumor drug rafenil.
T7804	Garenoxacin mesylate hydrate	Garenoxacin mesylate [USAN],BMS284756 (Mesylate hydrate)	Antibacterial
	Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strains.		Antibacterial
T2222	Carbinoxamine Maleate Salt	Lergefin,CarbinoxaMine Maleate	Histamine Receptor
	Carbinoxamine Maleate Salt (Lergefin) is an ethanolamine class of H1 antihistamines with mild antimuscarinic and sedative properties.		Histamine Receptor
T20824	Cyanox CY 1790	Lowinox 1790,Irganox 3790,Antioxidant 1790,Irganox-3790,DN 90	Others
	Cyanox CY 1790 (Irganox-3790) is an agent with antioxidant activity.		Others
TN1527	(-)-Corynoxidine	Corynoxidine	Antibacterial , AChE , Antifection
	(-)-Corynoxidine is an AChE inhibitor derived from tubers of Stephania succifera. Corynoxidine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus strains in di...		Antibacterial , AChE , Antifection
T25944	Phenoxyacetone	NSC-1876,NSC 1876,NSC1876	Others
	Phenoxyacetone (NSC-1876) is an inhibitor of acetylcholinesterase.		Others
TP1886L1	NoxA1ds acetate(1435893-78-9 free base)		NADPH-oxidase
	NoxA1ds acetate is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 : 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. Inhibits NOX1-derived O2- production in HT-29 human col...		NADPH-oxidase
T22678	3,5-Bis(4-nitrophenoxy)benzoic acid	Compound W	Gamma-secretase
	3,5-Bis(4-nitrophenoxy)benzoic acid (Compound W) is an inhibitor of γ-secretase. It also causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25).		Gamma-secretase